INDONESIAN JOURNAL OF PHARMACY
Vol 27 No 2, 2016

ANTI-OXIDANT AND ANTI-DIABETIC ACTIVITIES OF ETHANOLIC EXTRACT OF Primula denticulata FLOWERS

Hemlata Bhatt (Dept Pharmaceutical Sciences, H.N.B. Garhwal University, Srinagar-,Garhwal, Uttarakhand, India. 246174)
Sarla Saklani (Unknown)
Kumud Upadhayay (Unknown)

Article Info

Publish Date
01 Mar 2016

Abstract

The present investigation was carried out to focus on the anti-oxidant and anti-diabetic effect of ethanolic extract of flowers of  Primula denticulata by DPPH, ferrous chelating, reducing power assay and streptozotocin induced diabetes respectively. Dose selection was made on the basis of acute oral toxicity study (100mg/kg, 200mg/kg, 400mg/kg bodyweight) as per OECD guidelines 423.  The blood glucose levels were measured by using blood glucose measuring strips based on glucose-oxidase method. The extract showed significant anti-oxidant and anti-diabetic activity when compared with standard drug.Keywords:  Primula denticulata, anti-oxidant and anti-diabetic activity. 

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Journal Info
INDONESIAN JOURNAL OF PHARMACY
Website

Abbrev

3

Publisher

Universitas Gadjah Mada

Subject

Medicine & Pharmacology

Description

Indonesian Journal of Pharmacy (ISSN-e: 2338-9486, ISSN-p: 2338-9427), formerly Majalah Farmasi Indonesia (ISSN: 0126-1037). The journal had been established in 1972, and online publication was begun in 2008. Since 2012, the journal has been published in English by Faculty of Pharmacy Universitas ...