Biology, Medicine, & Natural Product Chemistry
Vol 14, No 2 (2025)

GC-MS Determination of Bioactive Components with Their Biological Activities of Olax subscorpioidea (Olacaceae)

Odoma, Saidi (Unknown)
Adekilekun, Ajibola Habeebulahi (Unknown)
Onohuean, Hope (Unknown)
Funso, Funso-Babarimisa (Unknown)
Oyewusi, Adekilekun Habeebat (Unknown)
Hamid, Abdulmumeen Amao (Unknown)



Article Info

Publish Date
31 Dec 2025

Abstract

Medicinal plants have been an integral part of healthcare, particularly in Africa, where over 80% of the population relies on traditional herbal medicine. This research focuses on Olax subscorpioidea, a plant recognized for its extensive pharmacological activities, including anti-inflammatory, antioxidant, antidiabetic, and analgesic properties. The study aimed to identify the bioactive compounds present in the leaf extract of O. subscorpioidea using Gas Chromatography-Mass Spectrometry (GC-MS) analysis. The plant was collected, dried, and extracted with methanol, leading to the identification of 199 compounds, including phenols, terpenoids, flavonoids, and fatty acids, some of which possess significant biological activities. Toxicological studies indicated a safe dosage with no adverse effects observed in mice. This research underscores the potential of O. subscorpioidea as a source of novel therapeutic agents, necessitating further isolation and characterization of its bioactive constituents to explore their pharmacological potentials comprehensively.

Copyrights © 2025






Journal Info

Abbrev

BIOMEDICH

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Description

BIOLOGY, MEDICINE, & NATURAL PRODUCT CHEMISTRY, this journal is published to attract and disseminate innovative and expert findings in the fields of plant, animal, and microorganism secondary metabolite, and also the effect of natural product on biological system as a reference source for ...