This study was motivated by the limited use of interactive learning media in science and social studies (IPAS), particularly in teaching the human digestive system in Grade V elementary school. Learning activities were still dominated by lectures and textbooks, resulting in low student engagement and difficulties in understanding abstract concepts. This research aimed to develop a Mystery Box learning media assisted by QR Code that meets the criteria of validity and practicality. The study employed a Research and Development (R&D) approach using the 4-D model (Define, Design, Develop, and Disseminate). The research was conducted at SD Negeri 182/I Hutan Lindung involving expert validators, teachers, and Grade V students. Data were collected through observation, interviews, validation questionnaires, and practicality questionnaires. The validation results indicated that the media was categorized as very valid, with a score of 96.66% from media experts, 96.66% from material experts, and 100% from language experts. The practicality test showed that the teacher’s response reached 94.28%, categorized as very practical. These findings demonstrate that the QR Code-assisted Mystery Box media is feasible and practical to be implemented in IPAS learning on the human digestive system topic in Grade V elementary school.
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