Objective: This research is an observational analytical study with a cross-sectional approach in adult patients diagnosed with sepsis in integrated inpatient wards and intensive care wards at Haji Adam Malik Hospital Medan. Methods: The subject sampling technique used was non-probability sampling with a consecutive sampling method where 115 subjects were required. Bivariate analysis used the Spearman correlation test on the Total Lymphocyte Count value and SOFA score with a 95% confidence interval, with a p-value <0.05 considered significantly significant. Results and Discussion: The results of the research on the first day found that the average lymphocyte count was 0.92 + 0.29 (0.78) and the average SOFA score was 9.96 + 2.88 (11), where an r-value of -0.783 was obtained, which indicates a high and significant negative relationship between lymphocyte count and SOFA score as a predictor of sepsis patients (p-value = 0.001, p <0.05). Conclusion: Lymphocyte count has a strong negative correlation with the SOFA score in adult patients diagnosed with sepsis in integrated inpatient wards and intensive care wards.
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