Jurnal Komunitas Farmasi Nasional
Vol. 5 No. 02 (2025): Jurnal Komunitas Farmasi Nasional

Pengaruh Pengenceran Nanokoloid Perak Hasil Biosintesis Menggunakan Ekstrak Tanaman Keladi Sarawak(Alocasia macrorrhizos (L.)) Sebagai Bahan Aktif Gel Melawan Staphylococcus aureus

Masykuroh, Athiah (Unknown)
Aprilia, Patrisia (Unknown)
Rizka Ananda, Nabila (Unknown)



Article Info

Publish Date
02 Mar 2026

Abstract

The study on evaluate the effect of dilution concentration of silver nanocolloids synthesized using Alocasia macrorrhizos (L.)) extract as the active ingredient in gel formulations on their antibacterial activity against Staphylococcus aureus has been conducted. The gel with undiluted nanocolloid was compared with the previous formulation containing 50% diluted nanocolloid. The gel was formulated using a Carbopol 940 base and evaluated for organoleptic properties, pH, homogeneity, viscosity, spreadability, and hedonic acceptance. Antibacterial activity was assessed using the disk diffusion method. The results showed that the gel met all physical parameters except viscosity. The antibacterial activity against Staphylococcus aureus was categorized as strong, with inhibition zones of 11.52 ± 0.10 mm (F1), 11.83 ± 0.19 mm (F2), and 12.44 ± 0.65 mm (F3). Increasing the nanocolloid concentration from 50% to 100% did not produce a significant difference in antibacterial activity.

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Journal Info

Abbrev

jkfn

Publisher

Subject

Medicine & Pharmacology Public Health

Description

Jurnal Komunitas Farmasi Nasional adalah jurnal akses terbuka dan peer-review yang diterbitkan oleh Akademi Farmasi Yarsi Pontianak. Jurnal ini diterbitkan dua kali per tahun pada bulan Juni dan Desember. Jurnal Komunitas Farmasi Nasional menerbitkan artikel penelitian di bidang farmasi dan ilmu ...