<![CDATA[Purpose: This study aims to examine the influence of substance abuse on the psycho-social health of youths in Taraba State, Nigeria, particularly focusing on emotional stability and self-esteem. Research Methodology: This study employed a quantitative approach using a cross-sectional survey design. Data were collected from 353 youths aged 15–35 years across the sixteen Local Government Areas of Taraba State using structured questionnaires. The sampling technique used was stratified random sampling to ensure representation across the study area. Data were analysed using descriptive statistics and simple linear regression through SPSS to determine the effect of substance abuse on emotional stability and self-esteem. Results: The results reveal a significant negative relationship between substance abuse and psychosocial wellbeing. Substance abuse significantly predicts lower emotional stability (? = ?0.385, p < .001) and lower self-esteem (? = ?0.269, p < .001). The findings indicate that higher levels of substance use are associated with emotional dysregulation, anxiety, feelings of guilt and worthlessness, and social withdrawal among youths. Conclusions: The study concludes that substance abuse significantly undermines the psycho-social health of youths in Taraba State, contributing to emotional instability, reduced self-esteem, and broader psychological distress that may reinforce cycles of dependency. Limitations: The study is limited by the cross-sectional design and reliance on self-reported data, which may affect generalizability. Contributions: The study provides empirical evidence to support the development of youth-cantered mental health interventions, community awareness programs, and improved rehabilitation services to reduce substance abuse and enhance youth wellbeing in Taraba State.]]>
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