Jambura Journal of Biomathematics (JJBM)
Vol. 7 No. 1: March 2026

Hemodynamic Modeling of Branch Retinal Artery Occlusion Involving Asymmetric Vascular Stenosis

Basuki Widodo (Department of Mathematics, Sepuluh Nopember Institute of Technology, Surabaya, Indonesia)
Ni Putu Dewi (Department of Mathematics, Sepuluh Nopember Institute of Technology, Surabaya, Indonesia)
Yuni Muarifadila (Department of Mathematics, Sepuluh Nopember Institute of Technology, Surabaya, Indonesia)
Annisa Sulistyaningtyasa (Department of Mathematics, Sepuluh Nopember Institute of Technology, Surabaya, Indonesia)
Arif Fatahillah (Department of Mathematics Education, University of Jember, Jember, Indonesia)
Tri Rahayuningsih (Department of Agroindustry Technology, University of Wijaya Kusuma Surabaya, Surabaya, Indonesia)



Article Info

Publish Date
30 Mar 2026

Abstract

The narrowing of retinal blood vessels, especially in conditions involving branch retinal artery occlusion (BRAO), can cause gradual and painless vision deterioration. Such vascular obstruction is also a contributing factor to eye stroke. This study investigates the influence of three asymmetric stenosis geometries, namely Bell--Cosine, Cosine--Overlapping, and Bell--Overlapping, on fluid flow characterized as Newtonian, incompressible, and steady. The mathematical formulation is derived from the Navier--Stokes equations, discretized using the Finite Volume Method (FVM) and solved through the Semi-Implicit Method for Pressure-Linked Equations (SIMPLE) algorithm. Numerical simulations are performed in MATLAB with variations in stenosis length. The results demonstrate how different geometric shapes and stenosis lengths affect blood flow rate and pressure distribution. Among all configurations, the Bell--Cosine geometry consistently produces a flow rate above the normal threshold and a pressure level below the normal range for each stenosis length ($40\,\mu\text{m}$, $50\,\mu\text{m}$, $60\,\mu\text{m}$, $70\,\mu\text{m}$), compared with the other geometries. For every geometric arrangement, stenosis length plays a role in altering the flow behavior and pressure field around the constriction, while the peak velocity and peak pressure remain essentially unchanged.

Copyrights © 2026






Journal Info

Abbrev

ejournal

Publisher

Subject

Computer Science & IT Decision Sciences, Operations Research & Management Mathematics Public Health

Description

The Jambura Journal of Biomathematics JJBM is a peer reviewed academic journal published by the Department of Mathematics, Faculty of Mathematics and Natural Sciences, Universitas Negeri Gorontalo, Indonesia. The journal is established with the vision of becoming a leading scientific publication in ...