PharmaCine: Journal of Pharmacy, Medical and Health Science
Vol. 5 No. 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science

Pengaruh Sumber Asam Basa terhadap Sifat Fisik dalam Formulasi Granul Effervescent : Tinjauan Pustaka

Reza Pratama (Pharmacy and Pharmaceutical Technology Scientific Group, Faculty of Pharmacy, Bhakti Kencana University, Bandung, Indonesia, 40614)
Ida Hasanah (Pharmacy and Pharmaceutical Technology Scientific Group, Faculty of Pharmacy, Bhakti Kencana University, Bandung, Indonesia, 40614)
Widya Nurasih (Pharmacy and Pharmaceutical Technology Scientific Group, Faculty of Pharmacy, Bhakti Kencana University, Bandung, Indonesia, 40614)
Novaliana Devianti Sagita (Pharmacy and Pharmaceutical Technology Scientific Group, Faculty of Pharmacy, Bhakti Kencana University, Bandung, Indonesia, 40614)



Article Info

Publish Date
28 Mar 2024

Abstract

Background: Indonesia has abundant natural resources, including types of herbal plants. Herbal plants in Indonesia have various health benefits and have been widely processed in the form of functional drinks. Aim:. To reduce the often undesirable taste and odor characteristics of herbal medicine, it can be further processed into derivative products that taste good and have a longer shelf life. One way is to process it into an effervescent preparation. Method: Searching and collecting journal information is carried out electronically, namely by accessing international and national journal search sites such as online from Pubmed, Google Scholar and Sciencedirect. by using the keywords "Effervescent Granules" and "Effervescent Herbal Drinks". Result: In effervescent granules there are acids and bases, the acids used are citric acid and tartaric acid which are acid components commonly used in effervescent granules. The use of a single acid will cause difficulties in its manufacture. The combination of citric acid and tartaric acid in effervescent granule preparations aims to simplify the process of making effervescent granule formulations. Conclusion: The results of existing literature studies show that the combination of acids in effervescent preparations greatly facilitates the process of forming effervescent granules. The use of different combinations of acid sources affects the physical properties of effervescent granules, including flow rate, dissolution time, pH and others. Sodium bicarbonate as a base source has the most significant influence on water content. The acid combination commonly used in making effervescent granules is citric acid andĀ tartaricĀ acid. Keywords: Effervescent granules, citric acid, tartaric acid, sodium bicarbonate

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Journal Info

Abbrev

pharmac

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

Description

PharmaCine: Journal of Pharmacy, Medical, and Health Sciences is a peer-reviewed journal dedicated to scientific publications in the fields of pharmacy, medicine, and health sciences. PharmaCine is published biannually, in March and September, by the Undergraduate Pharmacy Program, Faculty of Health ...