<![CDATA[Background: Urinary Tract Infection (UTI) is one of the most common bacterial infections requiring antibiotic therapy. Irrational use of antibiotics can lead to resistance and reduce treatment effectiveness. This study aimed to determine the pattern and rationality of antibiotic use in UTI patients at Sultan Imanuddin Hospital Pangkalan Bun using the Gyssens method.Methods: This research was descriptive-analytic with a retrospective approach on inpatient medical records in 2024. A total of 83 patients were included using purposive sampling. The rationality of antibiotic use was evaluated using the Gyssens method based on accuracy of indication, dosage, interval, route, and duration. Results: The most commonly used antibiotic group was cephalosporins (95.0%), with Ceftriaxone (70.4%) as the most frequently prescribed type, followed by Cefotaxime (16.0%) and Cefixime (4.9%). According to the Gyssens method, 41 patients (49.6%) were categorized as rational (category 0), while 42 patients (50.4%) were irrational, mostly due to inappropriate duration and antibiotic selection.Conclusion: The pattern of antibiotic use in UTI patients was dominated by cephalosporins. Based on the Gyssens method, the rationality rate of antibiotic use was 49.6%, indicating the need for improved antibiotic therapy monitoring in hospitals.]]>
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