Liquid waste from tofu production and rice washing that is directly discharged without prior treatment causes water pollution that negatively impacts the surrounding environment. Tofu wastewater and rice washing water contain relatively high levels of nitrogen (N), phosphorus (P), and potassium (K), making them suitable for use as raw materials in the production of liquid organic fertilizer (LOF) for celery plants. This study aimed to develop a design of Student Worksheets (LKPD) for the subtopic of Conventional Biotechnology Products for Grade X senior high school through a study on the utilization of LOF in celery using a hydroponic system. This research employed a mixed methods approach with a sequential mixed methods strategy. In the first stage, quantitative research was conducted using an experimental method. The results of the first stage served as the basis for the second stage, which involved a qualitative approach in the form of designing the LKPD for the subtopic of conventional biotechnology products. The experiment used a Completely Randomized Design (CRD) consisting of five treatments with three replications. The observed parameters included plant height, number of leaves, root length, fresh weight, and dry weight. The results showed that the combination of LOF from tofu wastewater and rice washing water had a significant effect on the growth of celery plants, with the combination treatment of 2.5 liters of tofu wastewater and 2.5 liters of rice washing water identified as the best treatment across all parameters, namely plant height, number of leaves, root length, fresh weight, and dry weight. The research findings were then integrated into the LKPD design and validated by experts as an LKPD that is appropriate for use in teaching conventional biotechnology for Grade X senior high school.
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