Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan
Vol. 4 No. 3 (2025): September: Jurnal Ilmiah Kedokteran dan Kesehatan

Formulasi Sediaan Bedak Tabur dari Rimpang Kencur (Kaempferia galanga L.) sebagai Antioksidan dengan Menggunakan Metode DPPH




Article Info

Publish Date
03 Jul 2025

Abstract

Free radicals can damage the skin and cause premature aging, so antioxidants are needed to protect the skin. Kencur rhizome (Kaempferia galanga L.) contains compounds that have potential as natural antioxidants. This study aims to develop a formulation of loose powder preparation from kencur rhizome simplisia with concentration variations of 4%, 6%, and 8%, and evaluate its physical quality and antioxidant activity using the DPPH method. The physical quality of the powder preparation included organoleptics, homogeneity, adhesion, pH, irritation, and hedonic test. The results showed that all formulations were organoleptically stable and homogeneous and the pH of the preparation was stable at 25°C but changed significantly at 40°C ± 2°C (p<0.05). Adhesion was less than optimal (p>0.05). The irritation test showed mild reactions in some panelists for F2 and F3. Hedonic test showed that F3 was most preferred by the panelists. Antioxidant activity of kencur rhizome extract (IC50 22.65 ppm), F1 (IC50 163.14 ppm), F2 (IC50 54.16 ppm), and F3 (IC50 35.48 ppm).

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Journal Info

Abbrev

klinik

Publisher

Subject

Medicine & Pharmacology Nursing Public Health

Description

Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan diterbitkan 3 (tiga) kali dalam satu tahun yaitu Edisi Januari, Mei, dan September. Jurnal Ilmiah Kedokteran dan Kesehatan menyajikan hasil penelitian dan tinjauan pustaka sehingga jurnal ini bermanfaat bagi dokter, pengambil kebijakan, tenaga ...