<![CDATA[Background: KL-6 serum was a glycoprotein biomarker of lung inflammation and epithelial damage. Waste workers at Supit Urang Landfill, Malang, Indonesia has a risk from occupational inhalation exposure such as bacterial bioaerosol, VOC, CH4, CO, H2S. This study analyzed serum KL-6 serum levels as inflammation biomarker according to length of exposure duration and type of work. Methods: The study design analytic experimental with cross-sectional approached. Total subject was 79 worker who grouped by exposure duration in 24 subjects on 1–5 years; 29 subjects on 5–10 years; 26 subjects on >10 years as. Others groups type of work consisted of 48 scavengers; 20 waste sorters as; 9 waste processors; 2 laboratories technicians. KL-6 levels were measured by ELISA. Anova and spearman-rho analysis was used for KL-6 serum level in each group. Results: KL-6 serum level was significantly (p = 0.000) increased in workers with >10 years of exposure (1170,3 ± 621,4 U/mL) compared to the others group. Scavengers have a significantly (p = 0,002) increased of KL-6 serum level (1049,6 ± 586,6 U/mL) compared to the others groups. Moderate correlation existed between exposure duration and KL-6 serum levels with positive result (r=0.470, p=0.000). Conclusion: The research found higher serum KL-6 levels after 10 years of exposure. Gas product exposure puts scavengers at danger of inhalation.]]>
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