WMJ (Warmadewa Medical Journal)
Vol 8 No 1 (2023): May 2023

The Maternal Serum Alpha-Fetoprotein for Congenital Anomalies Screening

Patria Dewi Pande (Stikes Wira Medika)
Jusak Nugraha (Airlangga University)



Article Info

Publish Date
31 May 2023

Abstract

Screening examination for maternal, especially serum, is a non-invasive examination of the fetus’s condition. During pregnancy, screening examinations are performed in women recommended for ultrasonography (USG), amniocentesis, or other obstetric interventions. There are three markers for maternal serum screening: alpha-fetoprotein, human chorionic gonadotropin (hCG), and unconjugated estriol. Maternal serum alpha-fetoprotein is useful for screening aneuploidies and neural tube defects. This examination, besides seeing congenital abnormalities, can be used for the risk of pregnancy complications such as placental insufficiency, intrauterine growth restriction, preeclampsia, and intrauterine fetal death. Laboratory methods for examining maternal serum alpha-fetoprotein are radioimmunoassay and microparticle capture enzyme immunoassay. Keywords: Screening, Pregnancy, Alpha-Fetoprotein, Laboratory

Copyrights © 2023






Journal Info

Abbrev

warmadewa_medical_journal

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

WMJ (Warmadewa Medical Journal) is the Journal of Medicine & Health, contains scientific articles (Original/ Research Articles, Review Articles, Case Reports) by academic community of the Faculty of Medicine and Health Sciences Warmadewa University, other Faculties of Medicine and Health Sciences ...