Global Medical and Health Communication
Vol. 13 No. 3 (2025): Accredited Sinta 2

Serum High-Density Lipoprotein-Cholesterol Concentration as Determinant of Poor Glycemic Control in Type 2 Diabetes Mellitus Patients at a Public Health Center in Jakarta, Indonesia

Yenny (Department of Pharmacology and Clinical Pharmacy, Faculty of Medicine, Universitas Trisakti, West Jakarta)
Patricia Budihartanti Liman (Department of Nutrition, Faculty of Medicine, Universitas Trisakti, West Jakarta)
Joice Viladelphia Kalumpiu (Department of Pharmacology and Clinical Pharmacy, Faculty of Medicine, Universitas Trisakti, West Jakarta)
Triasti Khusfiani (Department of Pharmacology and Clinical Pharmacy, Faculty of Medicine, Universitas Trisakti, West Jakarta)
Jihan Samira (Department of Microbiology, Faculty of Medicine, Universitas Trisakti, West Jakarta)
Arleen Devita (Department of Microbiology, Faculty of Medicine, Universitas Trisakti, West Jakarta)



Article Info

Publish Date
19 Dec 2025

Abstract

The risk factors for glycemic control in type 2 diabetes mellitus (T2DM) are poorly understood. This study assessed the prevalence of poor glycemic control and the predictive factors of poor glycemic control among T2DM outpatients in the community. This 30-day community-based cross-sectional study was conducted among ambulatory T2DM patients in Jakarta from May to June 2023. Data on age, sex, and level of education were collected by questionnaire, whereas data on body mass index, lipid profile, and HbA1c were obtained by measurement. Glycemic control was good if HbA1c <7 % and poor if HbA1c≥7%. The relationships between age, sex, level of education, body mass index, lipid profile, and glycemic control were determined using simple logistic regression. Multivariable logistic regression was used to determine the most influential risk factors of glycemic control. Poor glycemic control was found in 68.4% respondents, and obesity in 57.9% of respondents. After adjustment for age, level of education, and triglyceride concentration, the most influential factor for glycemic control was HDL concentration (aOR=4.43, 95% CI=1.19–16.5, p=0.027). Patients with T2DM with HDL <40 mg/dl had a 4.63 times significantly higher odds of poor glycemic control than those with HDL ≥40 mg/dl. This study found a high prevalence of poor glycemic control in the community setting among individuals with T2DM, with HDL concentration as the most significant predictor. Meanwhile, a triglyceride concentration of ≥150 mg/dl independently provided 58% greater protection against glycemic control (p=0.035), but the effect was not significant after adjustment (p>0.05). The high prevalence of poor glycemic control, dyslipidemia, and obesity in T2DM patients requires routine screening and monitoring accompanied by health education on lifestyle modification for risk factor control, thus minimizing the risk of complications.

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Journal Info

Abbrev

gmhc

Publisher

Subject

Description

Global Medical and Health Communication is a journal that publishes research articles on medical and health published every 4 (four) months (April, August, and December). Articles are original research that needs to be disseminated and written in English. Subjects suitable for publication include ...