Biofaal Journal
Vol 7 No 1 (2026): Biofaal Journal

Phytopharmaceutical Potential of Clove Tea Bags as an Antihyperuricemic Agent in a Hyperuricemic Rat Model

Adrien Jems Akiles Unitly (Biomedical Science Study Program, Department of Biology, Faculty of Science and Technology, Universitas Pattimura, Ambon - Indonesia)
Amos Killay (Biomedical Science Study Program, Department of Biology, Faculty of Science and Technology, Universitas Pattimura, Ambon - Indonesia)
Maria Nindatu (Biomedical Science Study Program, Department of Biology, Faculty of Science and Technology, Universitas Pattimura, Ambon - Indonesia)
Debby Dijola Moniharapon (Biological Sciences Study Program, Department of Biology, Faculty of Science and Technology, Universitas Pattimura, Ambon - Indonesia)
Veince Benjamin Silahooy (Biological Sciences Study Program, Department of Biology, Faculty of Science and Technology, Universitas Pattimura, Ambon - Indonesia)
Beatrix Belina Sikafir (Biological Sciences Study Program, Department of Biology, Faculty of Science and Technology, Universitas Pattimura, Ambon - Indonesia)
Mechiavel Moniharapon (Biological Sciences Study Program, Department of Biology, Faculty of Science and Technology, Universitas Pattimura, Ambon - Indonesia)
Theresia Natalia Seimahuira (Medical Education Study Program, Faculty of Medicine, Universitas Pattimura, Ambon - Indonesia)
Kezia Josawel Lesbatta (Biomedical Science Study Program, Department of Biology, Faculty of Science and Technology, Universitas Pattimura, Ambon - Indonesia.)
Eka Safitri Sillehu (Occupational Health and Safety Study Program, Department of Biology, Faculty of Science and Technology, Pattimura University, Ambon - Indonesia)
La Eddy (Biological Sciences Study Program, Department of Biology, Faculty of Science and Technology, Universitas Pattimura, Ambon – Indonesia)
Nia Doritha Laratmase (Biological Sciences Study Program, Department of Biology, Faculty of Science and Technology, Universitas Pattimura, Ambon – Indonesia)



Article Info

Publish Date
29 May 2026

Abstract

High protein dietary patterns, particularly those rich in animal protein containing high purine levels, may lead to hyperuricemia characterized by elevated blood uric acid levels. This study aimed to evaluate the phytopharmaceutical activity of clove tea bags on changes in blood uric acid levels in hyperuricemic Rattus norvegicus rats. The study employed a completely randomized design consisting of five treatment groups with three replications. The groups included a negative control without potassium bromate induction or clove tea administration, a positive control induced with 29 g potassium bromate to establish a hyperuricemia model, and three treatment groups induced with hyperuricemia followed by clove tea administration at doses of 0.234 g/head/day, 0.351 g/head/day, and 0.468 g/head/day for 14 days. Data were analyzed to determine differences in blood uric acid levels among groups. The results demonstrated that clove tea administration reduced blood uric acid levels, with the most effective dose being 0.234 g/head/day. These findings suggest that clove tea has potential as a natural therapeutic agent for managing hyperuricemia and contributes to the development of plant-based functional interventions.

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Journal Info

Abbrev

biofaal

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Materials Science & Nanotechnology Medicine & Pharmacology

Description

Biofaal Journal merupakan jurnal online yang menerima dan mempublikasikan tulisan-tulisan ilmiah dalam bentuk artikel hasil penelitian terbaru, short communication, maupun review terhadap artikel dari bidang keilmuan Biologi, Faal Tumbuhan, Faal Hewan, Faal Manusia dan Faal Olahraga. Biofaal Journal ...