Introduction: A serious intraocular infection called endophthalmitis can cause permanent blindness and severe vision impairment. Family preparedness as the primary caregiver is essential to successful home care because this disease necessitates sophisticated continuous care following hospital release. The purpose of this study was to investigate family preparedness for endophthalmitis patients' post-hospital care. Methods: Study design is a qualitative descriptive with a case study approach. Participants consisted of six families of endophthalmitis patients in the inpatient ward of Cicendo Eye Hospital, selected through purposive sampling. Data were collected through in-depth semi-structured interviews and analyzed using verbatim transcription, data reduction, coding, categorization, and theme development until data saturation was achieved. Results: The study identified four main themes: family knowledge and skills in patient care, family perceptions and emotional readiness in facing discharge, support from healthcare providers and resources in discharge planning, and barriers and challenges in providing home care. Family readiness was influenced by health literacy, prior caregiving experience, healthcare support, and caregiver burden. Conclusion: Family readiness is a dynamic process influenced by cognitive, emotional, and healthcare system factors. Family centered care approach plays a key role in strengthening family readiness through active involvement, effective communication, and practice-based education during hospitalization.
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