International Archives of Medical Sciences and Public Health
Vol. 7 No. 1 (2026): International Archives of Medical Sciences and Public Health

SURGICAL MANAGEMENT OF SUPRASELLAR GERMINOMA: INSIGHTS FROM A CRANIOTOMY CASE

Monica Halim (Department of Surgery, Faculty of Medicine, University of Riau, A Achmad Regional General Hospital, Riau, Indonesia)
Andrea Valentino (Neurosurgery Divison, Department of Surgery, Faculty of Medicine, University of Riau, A Achmad Regional General Hospital, Pekanbaru, Riau, Indonesia)
Agustiawan Agustiawan (Faculty of Medicine, Helvetia Health Institution, Medan, Sumatera Utara, Indonesia)



Article Info

Publish Date
08 Jun 2026

Abstract

Intracranial germinoma is a rare midline CNS tumor, most commonly arising in the suprasellar or pineal regions. Suprasellar lesions frequently cause hypothalamic–pituitary dysfunction, resulting in diabetes insipidus, endocrine abnormalities, and visual impairment. We report a 21-year-old man with a two-year history of progressive visual blurring and polyuria polydipsia that culminated in acute loss of consciousness. Imaging revealed a suprasellar mass, and clinical deterioration required intensive care admission. Craniotomy was performed for tumor decompression and histopathological diagnosis, confirming germinoma. Postoperative radiotherapy led to recovery of consciousness after the third session and marked tumor regression to approximately 1 cm, demonstrating the tumor’s high radiosensitivity. Despite favorable oncologic response, residual deficits persisted, including left-sided visual blurring, complete right-eye blindness, severe hypocortisolemia, and low prolactin levels requiring hormone replacement therapy. This case emphasizes the importance of early diagnosis, individualized treatment, and multidisciplinary management to achieve tumor control while addressing long term neurological and endocrine sequelae. Survivorship-focused care integrating endocrinology, rehabilitation, psychosocial support, and adherence monitoring is essential, particularly in resource-limited settings, to improve treatment continuity, reduce complications, and enhance quality of life among young brain tumor survivors.

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Journal Info

Abbrev

iamsph

Publisher

Subject

Health Professions Medicine & Pharmacology Nursing Public Health

Description

International Archives of Medical Sciences and Public Health is a peer-reviewed journal dedicated to disseminating and discussing scientific literature and other health-related research. This journal is intended to serve as a forum for communication between stakeholders in health research, including ...