This study aims to analyze the roles of mothers and fathers in guiding Islamic spirituality and health among children with disabilities. This research uses a systematic literature review approach by analyzing peer-reviewed articles published between 2020 and 2025. The findings reveal that parenting grounded in Islamic spiritual values, particularly the concept of children as a divine trust (amanah), significantly contributes to family resilience and child well-being. Modeling behavior and direct religious practices are identified as the most effective methods for spiritual development. In addition, religious coping plays a crucial role in reducing parental stress and improving psychological well-being. The roles of mothers and fathers are complementary, where mothers act as primary caregivers and fathers support decision-making and family stability. This study emphasizes the importance of integrating spiritual dimensions into parenting strategies for children with disabilities.Keyword: Islamic spirituality; disability; parenting; religious coping
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