<![CDATA[Pain during invasive medical procedures is a major stressor for preschool children and may trigger physiological responses such as oxygen saturation decline due to crying and anxiety. This study aimed to analyze the effect of behavioural intervention on pain scale and oxygen saturation in preschool children undergoing intravenous procedures. This research was conducted using a quasi-experimental post-test only control group design. A total of 80 children aged 3–6 years undergoing intravenous insertion at RSI Jemursari Surabaya were selected through purposive sampling and divided equally into intervention and control groups. Pain intensity was assessed using the FLACC Scale, while oxygen saturation was measured using a pulse oximeter. Mann–Whitney U test was used for statistical analysis. The mean pain score in the intervention group (3.44) was significantly lower than in the control group (7.57). Meanwhile, the mean oxygen saturation in the intervention group (98%) was higher than in the control group (94.12%). Statistical analysis showed a significant difference between both variables (p=0.001). Behavioural intervention is effective in reducing pain and preventing oxygen desaturation in preschool children during invasive procedures. This intervention can be recommended as a non-pharmacological approach in pediatric nursing practice.]]>
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