Jurnal Ilmiah Farmasi
Vol. 22 No. 1 (2026): Jurnal Ilmiah Farmasi

Kajian Penggunaan Antidiabetik dan Hubungannya Dengan Kontrol Glikemik Pada Pasien Diabetes Mellitus Tipe II Dengan Nefropati Diabetik

Oktaviani, Emy (Unknown)
Indriani, Lusi (Unknown)
Kholilah , Siti (Unknown)



Article Info

Publish Date
31 May 2026

Abstract

Background: Diabetes mellitus (DM) is a metabolic disorder characterized by increased blood sugar levels (> 200 mg/dL). It occurs due to impaired insulin secretion, decreased insulin sensitivity, or a combination of both factors. DM is a chronic degenerative disease that necessitates long-term treatment and can significantly impact kidney function, particularly in patients with diabetic nephropathy. Objective: This study aims to examine the profile of antidiabetic medications, glycemic control, and the correlation between the pattern of antidiabetic use and glycemic control.Methods: This study employed a cross-sectional design with retrospective data derived from medical records.Results: Among the 104 patients who met the inclusion criteria, the most predominant age group was over 44 years (94.2%), with a slight female predominance (51%). A majority of the patients exhibited normal nutritional status, with a body mass index (BMI) ranging from 18.5 to 24.9 (52.9%). The most common complications were macrovascular, including hypertension, stroke, coronary heart disease, diabetic ketoacidosis, dyslipidemia, and gangrene, affecting 75% of the patients. Conclusion: Statistical analysis using the chi-square test revealed no significant relationship between the pattern of antidiabetic and the glycemic control (p-value = 0.558). This finding suggests that the use of Glycuidone alone, as well as the combination of insulin glargine and aspart, demonstrates good efficacy in achieving glycemic control.

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Journal Info

Abbrev

JIF

Publisher

Subject

Medicine & Pharmacology

Description

JIF merupakan jurnal yang dikelola oleh Prodi Farmasi Universitas Islam Indonesia, dan diterbitkan dua kali dalam setahun. Jurnal ini dirancang sebagai sarana publikasi penelitian yang mencakup secara rinci sejumlah topik dalam bidang farmasi yang berkaitan dengan farmasi sains dan teknologi serta ...