KESANS : International Journal of Health and Science
Vol 5 No 8 (2026): KESANS: International Journal of Health and Science

Determinants of Antihypertensive Medication Adherence among Hemodialysis Patients with Chronic Kidney Disease in Jambi Province, Indonesia

Desti Indri Yani (Faculty of Medicine and Health Sciences, Universitas Jambi, Indonesia)
Ummi Kalsum (Faculty of Medicine and Health Sciences, Universitas Jambi, Indonesia)
Willia Novita Eka Rini (Faculty of Medicine and Health Sciences, Universitas Jambi, Indonesia)
Asparian Asparian (Faculty of Medicine and Health Sciences, Universitas Jambi, Indonesia)
Muldiasman Muldiasman (Faculty of Medicine and Health Sciences, Universitas Jambi, Indonesia)
Armaidi Darmawan (Faculty of Medicine and Health Sciences, Universitas Jambi, Indonesia)



Article Info

Publish Date
12 Jun 2026

Abstract

Introduction: Chronic kidney disease patients undergoing hemodialysis commonly experience hypertension requiring long-term antihypertensive therapy. Poor medication adherence may increase complications and mortality. Objective: This study aimed to analyze factors associated with antihypertensive medication adherence among chronic kidney disease patients undergoing hemodialysis in Jambi Province, Indonesia. Method: This analytical observational study used a cross-sectional design. A total of 193 respondents were recruited using consecutive sampling. Data were collected using structured questionnaires, including the Morisky Medication Adherence Scale-8 (MMAS-8), knowledge questionnaire, and family support questionnaire. Data were analyzed using univariate, bivariate, and multivariate logistic regression analyses. Results and Discussion: A total of 53.4% of respondents were non-adherent to antihypertensive medication. Bivariate analysis showed no significant association between independent variables and medication adherence (p>0.05). However, knowledge demonstrated a tendency toward association with adherence behavior. Respondents with good knowledge had 2.44 times higher odds of adherence compared with respondents with poor knowledge (Adjusted OR=2.440; 95% CI: 0.887–6.716; p=0.084). Family support remained in the final model as a contributing variable. Conclusion: No statistically significant determinants of antihypertensive medication adherence were identified. However, knowledge and family support showed a tendency to contribute to medication adherence among hemodialysis patients and may be important targets for future interventions

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Journal Info

Abbrev

kesans

Publisher

Subject

Chemistry Health Professions Medicine & Pharmacology Physics Public Health

Description

KESANS : International Journal of Health and Science provides a means for ongoing discussion of the relevant issues that fall within the focus and scope of the journal that can be examined empirically. This journal publishes research articles in the medicine, Nursing, Midwifery, Public Health, ...