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All Journal KESANS : International Journal of Health and Science
Ummi Kalsum
Faculty of Medicine and Health Sciences, Universitas Jambi, Indonesia
Chemistry Health Professions Medicine & Pharmacology Physics Public Health

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Determinants of Antihypertensive Medication Adherence among Hemodialysis Patients with Chronic Kidney Disease in Jambi Province, Indonesia Desti Indri Yani; Ummi Kalsum; Willia Novita Eka Rini; Asparian Asparian; Muldiasman Muldiasman; Armaidi Darmawan
Jurnal KESANS : Kesehatan dan Sains Vol 5 No 8 (2026): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v5i8.645

Abstract

Introduction: Chronic kidney disease patients undergoing hemodialysis commonly experience hypertension requiring long-term antihypertensive therapy. Poor medication adherence may increase complications and mortality. Objective: This study aimed to analyze factors associated with antihypertensive medication adherence among chronic kidney disease patients undergoing hemodialysis in Jambi Province, Indonesia. Method: This analytical observational study used a cross-sectional design. A total of 193 respondents were recruited using consecutive sampling. Data were collected using structured questionnaires, including the Morisky Medication Adherence Scale-8 (MMAS-8), knowledge questionnaire, and family support questionnaire. Data were analyzed using univariate, bivariate, and multivariate logistic regression analyses. Results and Discussion: A total of 53.4% of respondents were non-adherent to antihypertensive medication. Bivariate analysis showed no significant association between independent variables and medication adherence (p>0.05). However, knowledge demonstrated a tendency toward association with adherence behavior. Respondents with good knowledge had 2.44 times higher odds of adherence compared with respondents with poor knowledge (Adjusted OR=2.440; 95% CI: 0.887–6.716; p=0.084). Family support remained in the final model as a contributing variable. Conclusion: No statistically significant determinants of antihypertensive medication adherence were identified. However, knowledge and family support showed a tendency to contribute to medication adherence among hemodialysis patients and may be important targets for future interventions
Behavioral and Cardiometabolic Factors Associated with Prediabetes Among Adolescents Nurul Anggini; Ilham Ilham; Ummi Kalsum
Jurnal KESANS : Kesehatan dan Sains Vol 5 No 9 (2026): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v5i9.670

Abstract

Introduction: Prediabetes among adolescents is an emerging public health problem due to its increasing prevalence and potential progression to type 2 diabetes mellitus. Various behavioral and cardiometabolic factors have been reported to contribute to the development of prediabetes; however, existing evidence remains fragmented. Objective: This study aimed to systematically review and synthesize current evidence regarding dietary, behavioral, obesity-related, and cardiometabolic factors associated with prediabetes among adolescents. Method: A Systematic Literature Review (SLR) was conducted following the PRISMA 2020 guidelines. Literature searches were performed in PubMed, Scopus, ScienceDirect, and Google Scholar for studies published between 2021 and 2026. Eligible studies included original research involving adolescents aged 10–19 years and reporting factors associated with prediabetes, obesity, overweight, or related metabolic disorders. The methodological quality of the included studies was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist. Results and Discussion: A total of 11 studies met the eligibility criteria and were included in the review. The findings identified unhealthy dietary patterns, low physical activity, sedentary behavior, obesity, cardiometabolic abnormalities, and sugar-sweetened beverage consumption as factors associated with prediabetes among adolescents. Obesity emerged as the most consistent predictor of prediabetes, while behavioral factors such as junk food consumption, prolonged screen time, and inadequate physical activity contributed indirectly through increased obesity risk. Conclusion: Prediabetes among adolescents is influenced by multiple behavioral and cardiometabolic factors, with obesity serving as the primary intermediary determinant. Comprehensive interventions focusing on healthy dietary behaviors, physical activity promotion, obesity prevention, and early metabolic screening are essential to reduce the future burden of prediabetes and type 2 diabetes mellitus among adolescents
Host, Agent, and Environmental Determinants of Postoperative Nausea and Vomiting Following Spinal Anesthesia: A Systematic Review Using the Epidemiological Triad Framework Mutia Putri Anggraini; Humaryanto Humaryanto; Ummi Kalsum
Jurnal KESANS : Kesehatan dan Sains Vol 5 No 9 (2026): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v5i9.672

Abstract

Introduction: Postoperative nausea and vomiting (PONV) remains one of the most common complications following spinal anesthesia and may adversely affect patient recovery, satisfaction, and healthcare outcomes. Objective: This study aimed to identify and synthesize host, agent, and environmental determinants associated with PONV following spinal anesthesia using the Epidemiological Triad Framework. Method: A systematic review was conducted according to the PRISMA 2020 guidelines. Literature searches were performed in PubMed, Scopus, ScienceDirect, and Google Scholar for studies published between 2023 and 2025. Eligible studies included randomized controlled trials, cohort studies, observational studies, and quasi-experimental studies involving patients undergoing spinal anesthesia. Data were extracted, critically appraised using Joanna Briggs Institute tools, and synthesized narratively. Results and Discussion: Twelve studies met the inclusion criteria. The most frequently reported host determinants were previous history of PONV, motion sickness, female sex, younger age, and elevated body mass index. Agent-related determinants included opioid exposure, intrathecal morphine, and intrathecal fentanyl, whereas dexamethasone, propofol, clonidine, and opioid-sparing analgesic techniques demonstrated protective effects. Environmental determinants included cesarean section, prolonged fasting, inadequate perioperative hydration, and intraoperative nausea and vomiting. Conclusion: PONV following spinal anesthesia is a multifactorial condition resulting from interactions among host, agent, and environmental factors. Early risk assessment and comprehensive preventive strategies are essential to reduce PONV incidence and improve postoperative outcomes
Comparative Effectiveness of Exercise-Based Interventions on Pain and Physical Function in Knee Osteoarthritis: A Narrative Review of Recent Evidence Syntheses Novin Tri Wahyuni; Ummi Kalsum; Humaryanto Humaryanto; Guspianto Guspianto
Jurnal KESANS : Kesehatan dan Sains Vol 5 No 9 (2026): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v5i9.673

Abstract

Introduction: Knee osteoarthritis (KOA) is a leading cause of pain and disability among older adults, with exercise-based therapy widely recommended as first-line management. However, findings vary considerably across intervention types, comparators, and outcome measures. Objective: To synthesize and compare recent high-quality evidence regarding the effectiveness of Pilates, traditional Chinese exercise, and multi-modal physiotherapy on pain and physical function in KOA patients. Methods: A narrative synthesis was conducted using three recent evidence sources: a 2025 meta-analysis of Pilates exercise (11 RCTs, n=476), a 2023 meta-analysis of traditional Chinese exercise (17 RCTs, n=1,174), and the MOA Trial evaluating manual and exercise physiotherapy (n=206). Primary outcomes were pain (VAS, NPRS) and physical function (WOMAC) Results and Discussion: Pilates reduced pain versus no intervention (SMD −1.09; 95% CI −2.04 to −0.14) but showed no significant superiority over conventional exercise. Traditional Chinese exercise improved WOMAC pain, stiffness, and function compared with controls, with Tai Chi demonstrating the most consistent benefit. In the MOA Trial, manual physiotherapy produced the greatest WOMAC reduction (−28.5 points; 95% CI −47.8 to −9.2) Conclusion: All three modalities provided modest benefits, though evidence certainty ranged from very low to moderate with substantial heterogeneity. Individualized exercise prescription based on patient preference and access to supervised therapy is recommended over a single universal approach
Co-Authors Armaidi Darmawan Asparian Asparian Desti Indri Yani Guspianto Guspianto Humaryanto Humaryanto Ilham Ilham Muldiasman, Muldiasman Mutia Putri Anggraini Novin Tri Wahyuni Nurul Anggini Willia Novita Eka Rini