This study addresses the limitation of single-objective content-based image retrieval in medical imaging, which fails to consider multiple clinical preferences such as image quality. The objective is to develop a preference-driven retrieval system for COVID-19 chest radiography images. A hybrid approach is proposed by integrating a Dual-Head DenseNet-121 model for feature extraction and quality regression with a multi-objective skyline query algorithm for retrieval optimization. The system evaluates multiple image quality dimensions, including sharpness, contrast, exposure, signal-to-noise ratio, and entropy. Experimental results demonstrate that the proposed method achieves 100% Pareto efficiency and improves diversity and hypervolume coverage compared to conventional methods. This approach provides a more flexible and effective multi-objective retrieval mechanism, contributing to the advancement of intelligent medical image retrieval systems in computer science.
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