JPSCR : Journal of Pharmaceutical Science and Clinical Research
Vol 11, No 1 (2026)

Drug-Related Problems Leading to Hospitalization: A Literature Review

Kharisma, Annisa Nur (Unknown)
Rahmawati, Fita (Unknown)
Siswanto, Soni (Unknown)



Article Info

Publish Date
31 Mar 2026

Abstract

Background: Drug-related problems (DRPs) are described as problems associated with medications that can lead to treatment failure and may also cause hospital admissions. The novelty of this study is that it supplements previous research data with the latest data on DRPs leading to hospital stays, specifically articles published between 2021 and 2025. Objective: This study aims to identify the prevalence of hospitalization due to DRPs, the types of DRPs that lead to hospital admissions, the medications involved, and the risk factors for DRPs. Methods: A literature search was conducted across the PubMed, ScienceDirect, and Scopus databases, limiting publication years to 2021-2025. Results: In the 12 studies reviewed, the frequency of hospitalization due to DRP varied between 5,0% to 57,9%. Adverse drug reactions (ADRs), non-compliance, drug interactions, dosing errors, and incomplete therapy indication were the most common types of DRPs that lead to hospitalization. The drugs most commonly involved in DRPs were antidiabetic agents, cardiovascular agents, diuretics, and antineoplastic agents. Age, polypharmacy, and the number and severity of comorbidities were identified as primary risk factors for hospitalization caused by DRPs. Conclusion: The frequency of hospitalization due to DRP varied between 5,0% to 57,9%. Factors such as age, number of medications, and comorbidities influence the frequency of DRPs.

Copyrights © 2026






Journal Info

Abbrev

jpscr

Publisher

Subject

Environmental Science Public Health

Description

Journal of Pharmaceutical Science And Clinical Research (e-ISSN 2503-331x) offers a forum for publishing the original research articles, review articles from contributors, and the novel technology news related to pharmaceutical science and clinical research. Scientific articles dealing with natural ...