AcTion: Aceh Nutrition Journal
Vol 11, No 2 (2026): June

Risk factors for preeclampsia: A case-control study in Makassar City and Gowa Regency, Indonesia

Andi Sitti Rahma (School of Medicine, Universitas Islam Negeri Alauddin Makassar)
Rini Fitriani (School of Medicine, Universitas Islam Negeri Alauddin Makassar)
Sari Ifdiana Jalal (RSUD Haji Makassar)
Syarifah Intan Nurfitri (School of Medicine, Universitas Islam Negeri Alauddin Makassar)



Article Info

Publish Date
02 Jun 2026

Abstract

Preeclampsia remains a serious pregnancy complication with a high prevalence in Indonesia. This case-control study, conducted in Makassar City and Gowa Regency (August–December 2024), aimed to analyze the risk factors for preeclampsia in 78 pregnant women (>20 weeks gestation), diagnosed based on hypertension and proteinuria. Data on obstetric history, diet (FFQ), and anthropometrics were collected, including serum zinc levels measured using ELISA. Independent t-tests indicated a significantly higher pre-pregnancy Body Mass Index (BMI) in the preeclampsia group (p<0.05). A Chi-square test revealed that a history of preeclampsia served as an absolute predictor within this sample (95% CI: ∞). Multivariate Binary Logistic Regression showed that Weight Gain was the only statistically significant independent risk factor for preeclampsia incidence (p=0.045), with the risk category yielding an Odds Ratio (OR) of 2.928 (95% CI: 1.022–8.387). Other variables, including BMI, were not significant (p>0.05). Dietary patterns (fish intake) also showed an association with preeclampsia in preeclampsia women (p=0,022; OR 9.909 and 95% CI 1.396-70.348). The conclusion is that a history of preeclampsia is an absolute predictor in this study sample. There was a relationship between weight gain during pregnancy and fish intake with the incidence of preeclampsia in the study area.

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Journal Info

Abbrev

an

Publisher

Subject

Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

AcTion: Aceh Nutrition Journal merupakan jurnal gizi dan kesehatan dengan E-ISSN 2548-5741 dan ISSN 2527-3310. Jurnal ini bertujuan untuk meningkatkan kemampuan dalam penyampaian hasil penelitian sebagai media yang dapat digunakan untuk meregistrasi, mendiseminasi, dan mengarsipkan karya peneliti ...