The high unemployment rate among vocational high school graduates indicates that entrepreneurial interest remains a critical issue requiring empirical investigation. Previous studies have generally examined entrepreneurship knowledge, digital literacy, and entrepreneurial mindset separately, while limited evidence explains their simultaneous contribution to entrepreneurial interest among vocational students within the framework of the Theory of Planned Behavior. Addressing this gap, the present research investigates the influence of entrepreneurship knowledge, digital literacy, and entrepreneurial mindset on the entrepreneurial interest of Grade XI students at SMKS Budi Agung Medan in the 2025/2026 academic year. A quantitative explanatory approach was employed using a survey design involving 99 respondents selected from a population of 130 students through proportionate stratified random sampling based on the Slovin formula. Data were collected using questionnaires and school documentation, then analyzed through multiple linear regression with SPSS version 29 following validity, reliability, and classical assumption testing. The findings reveal that entrepreneurship knowledge (β = 0.340; p = 0.001), digital literacy (β = 0.301; p = 0.001), and entrepreneurial mindset (β = 0.153; p = 0.001) each exert a positive and significant effect on entrepreneurial interest. Simultaneously, the three variables significantly influence entrepreneurial interest (F = 29.396; p < 0.001) and explain 46.5% of its variance (Adjusted R² = 0.465). These findings reinforce the Theory of Planned Behavior by demonstrating that cognitive competence, digital capability, and entrepreneurial mindset collectively strengthen students' entrepreneurial intentions while providing practical implications for entrepreneurship education in vocational schools.
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