Jurnal Kedokteran Diponegoro
Vol 15, No 4 (2026): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)

ASSOCIATION BETWEEN ADMISSION D-DIMER LEVELS AND MORTALITY IN COVID-19

Amanatus Solikhhah (Department of Clinical Pathology, Faculty of Medicine, Ahmad Dahlan University)
Rizka Ariani (Department of Microbiology, Faculty of Medicine, Ahmad Dahlan University, Indonesia)
Mulat Muliasih (Department of Clinical Pathology, Faculty of Medicine, Malahayati University, Indonesia)



Article Info

Publish Date
01 Jul 2026

Abstract

Background: It is possible that specific laboratory test results could indicate the likelihood of death from COVID-19. Objective: The main goal of this research was to figure out if measuring D-dimer levels could help forecast the likelihood of death for individuals suffering from COVID-19. Methods: A backward-looking study of a group of people based on observations, encompassing 317 individuals, was conducted utilizing existing data extracted from the health documents of COVID-19 inpatients. The concentration of D-dimer was acquired via patient's blood test results upon initial admittance to the medical facility. Following this, patients were divided into two categories: those who lived (comprising 252 individuals) and those who did not (consisting of 66 individuals), according to the end result. Proportions and central values were assessed employing Kolmogorov-Smirnov. Logistic regression was applied to ascertain if there exists a noteworthy disparity in D-dimer concentrations among different mortality statuses. Results: The cohort that did not survive showed a notably elevated presence of D-dimer (Odds Ratio 6.480 ;p<0.001). Conclusion: The starting assessment of D-dimer levels might be useful in spotting individuals who face increased vulnerability and help guide choices concerning critical care management.

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Journal Info

Abbrev

medico

Publisher

Subject

Medicine & Pharmacology

Description

JKD : JURNAL KEDOKTERAN DIPONEGORO ( ISSN : 2540-8844 ) adalah jurnal yang berisi tentang artikel bidang kedokteran dan kesehatan karya civitas akademika dari Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang dan peneliti dari luar yang membutuhkan publikasi . ...