UMI Medical Journal
Vol 11 No 1 (2026): UMI Medical Journal

Management of Orbital Complications Based on Chandler Classification Stage II-IV in Pediatric Sinusitis: A Systematic Review

Fadelia Meutia Ananda (Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia)
Syifa Safira Nabila Putri (Faculty of Medicine, Universitas Islam Indonesia, Yogyakarta, Indonesia)
Aisyah Muthmainnah Budu (Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia)
Nuzulina Safira Hapsari Sunanto (Faculty of Medicine, Universitas Islam Indonesia, Yogyakarta, Indonesia)



Article Info

Publish Date
30 Jun 2026

Abstract

Background: Orbital complications are the most common sequelae of pediatric sinusitis (70–85%) and can lead to vision loss or intracranial issues if untreated. Irreversible vision loss occurs in 3–11% of advanced cases. Objective: To review current evidence on medical versus surgical treatment for Chandler Stage II–IV orbital complications in pediatric sinusitis, particularly since there is no clear guideline on when urgent surgery is required and when antibiotics alone are sufficient. Methods: A systematic review (2015–2025) was conducted via PubMed, Scopus, and ScienceDirect. Included studies involved patients <18 years with Stage II–IV complications. Data on treatments, outcomes, and risk of bias (Newcastle–Ottawa Scale) were analyzed. Results: Thirty-three studies (>16,700 patients) were included. Stage II was successfully treated with antibiotics alone in >90% of cases. In Stage III, 35–50% required surgery, especially with abscess ≥3.6 mm, vision changes, or poor response to antibiotics. Stage IV nearly always required urgent surgery. Stage-based treatment improved vision, motility, and proptosis, with no reported deaths. Conclusion: Chandler staging effectively guides treatment. Antibiotics suffice for Stage II; surgery is often needed for Stage III–IV. Timely, evidence-based care helps prevent permanent vision loss.

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Journal Info

Abbrev

umimedicaljournal

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology

Description

Umi Medical Journal (UMEDJ) is a field of health in the broadest sense such as medicine, public health, nursing, midwifery, pharmacy, health psychology, nutrition, biomedical sciences. ...