Indonesian Journal of Global Health Research
Vol. 8 No. 1 (2026): Indonesian Journal of Global Health Research

Evaluation of aPTT and PT Results: A Comparison Between Point-of-Care Testing and Optical Fully Automatic Methods

Herna Wahyuni (Universitas Sumatera Utara)
Dewi Indah Sari Siregar (Universitas Sumatera Utara & Prof. Dr. Chairuddin P Lubis Universitas Sumatera Utara Hospital)
Ranti Permatasari (Universitas Sumatera Utara & Adam Malik Hospital)
Nindia Sugih Arto (Universitas Sumatera Utara & Adam Malik Hospital)
Malayana Rahmita Nasution (Universitas Sumatera Utara & Adam Malik Hospital)
Jelita Siregar (Universitas Sumatera Utara & Prof. Dr. Chairuddin P Lubis Universitas Sumatera Utara Hospital & Adam malik Hospital)



Article Info

Publish Date
26 Oct 2025

Abstract

A coagulometer is a tool used to check coagulation parameters, such as prothrombin time (PT) and activated partial thromboplastin time (aPTT), for which there are currently various detection methods. Examining PT and aPTT coagulation function requires a fast turnaround time and immediate results because the stability of coagulation factors is less than four hours, so a fast and precise examination is needed. Point-of-care testing (POCT) is a good alternative. This study aimed to determine the difference in aPTT and PT values between POCT and optical fully automatic. This comparison will be useful when selecting coagulometer devices. Methods: This study used a cross-sectional study with a non-probabilistic sample of 100 citrate samples. Each sample was tested for aPTT and PT using POCT and optical fully automatic testing. The results of each examination were analyzed using the Mann–Whitney, Bland-Altman Plot, and correlation statistical tests. In this study, precision tests were also carried out on both methods. methods. There was a significant difference (p < 0.001) in the comparative test results for the aPTT and PT values obtained using the POCT method compared to the optical fully automatic method. The average difference between the two methods was 6.6 seconds for the aPTT parameter and 4.98 for the PT parameter. Fourteen samples were found to have different interpretation values for the aPTT parameter, and 28 samples for the PT parameter. There is a significant difference between the POCT method and the optical fully automatic method. The precision test on the POCT method produced good results.

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Journal Info

Abbrev

IJGHR

Publisher

Subject

Description

Indonesian Journal of Global Health Research is a open access, peer reviewed and refereed international journal. Indonesian Journal of Global Health Research aim to publish original research paper devoted to various area of all health sciences. Indonesian Journal of Global Health Research provides a ...