SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN
Vol 17, No 1 (2026): June 2026

Preoperative anemia and malnutrition predict postoperative complications in stage III colorectal cancer: a cross‑sectional study

Vito Mahendra (Department of Surgery, Faculty of Medicine, Universitas Islam Sultan Agung, Semarang Department of Doctoral Biomedical Science, Faculty of Medicine, Universitas Islam Sultan Agung, Semarang)
Naufal Aditya Ramadhan (Faculty of Medicine, Universitas Islam Sultan Agung, Semarang)
Mohammad Dhanny Akbar (Faculty of Medicine, Universitas Islam Sultan Agung, Semarang)
Abdullah Rizky (Faculty of Medicine, Universitas Islam Sultan Agung, Semarang)
Chodidjah Chodidjah (Department of Doctoral Biomedical Science, Faculty of Medicine, Universitas Islam Sultan Agung, Semarang Department of Anatomy, Faculty of Medicine, Universitas Islam Sultan Agung, Semarang)



Article Info

Publish Date
27 Jul 2026

Abstract

Colorectal cancer remains a major cause of morbidity and mortality. We conducted a cross‑sectional observational study of 65 consecutive stage III colorectal cancer patients from medical records at Sultan Agung Islamic Hospital (data collected 3–27 Dec 2024) to examine associations between treatment, preoperative haemoglobin, BMI‑defined nutritional status, CEA, Karnofsky Performance Status, and postoperative complications. Postoperative complications occurred in 11/14 (78.6%) patients with mild malnutrition, 2/6 (33.3%) with moderate malnutrition, and 8/8 (100.0%) with severe malnutrition; malnutrition was significantly associated with complications (p = 0.016). Among anaemic patients, 24/26 (92.3%) experienced complications, and anaemia was also significantly associated with complications (p = 0.020). CEA and Karnofsky Index were not significantly associated with postoperative complications. These findings indicate that preoperative anaemia and malnutrition are important predictors of postoperative morbidity in stage III colorectal cancer and support routine preoperative screening and timely correction of haemoglobin and nutritional deficits to improve surgical readiness and perioperative outcomes.

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Journal Info

Abbrev

sainsmedika

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Sains Medika is journal of medicine and health, is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from Biomedical Sciences, Public Health, Clinical Sciences, and Medical Education to integrate researches in all aspects of human health. This journal ...