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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN
Abdullah Rizky
Faculty of Medicine, Universitas Islam Sultan Agung, Semarang
Health Professions Medicine & Pharmacology

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Preoperative anemia and malnutrition predict postoperative complications in stage III colorectal cancer: a cross‑sectional study Vito Mahendra; Naufal Aditya Ramadhan; Mohammad Dhanny Akbar; Abdullah Rizky; Chodidjah Chodidjah
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 17, No 1 (2026): June 2026
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v17i1.43739

Abstract

Colorectal cancer remains a major cause of morbidity and mortality. We conducted a cross‑sectional observational study of 65 consecutive stage III colorectal cancer patients from medical records at Sultan Agung Islamic Hospital (data collected 3–27 Dec 2024) to examine associations between treatment, preoperative haemoglobin, BMI‑defined nutritional status, CEA, Karnofsky Performance Status, and postoperative complications. Postoperative complications occurred in 11/14 (78.6%) patients with mild malnutrition, 2/6 (33.3%) with moderate malnutrition, and 8/8 (100.0%) with severe malnutrition; malnutrition was significantly associated with complications (p = 0.016). Among anaemic patients, 24/26 (92.3%) experienced complications, and anaemia was also significantly associated with complications (p = 0.020). CEA and Karnofsky Index were not significantly associated with postoperative complications. These findings indicate that preoperative anaemia and malnutrition are important predictors of postoperative morbidity in stage III colorectal cancer and support routine preoperative screening and timely correction of haemoglobin and nutritional deficits to improve surgical readiness and perioperative outcomes.
Co-Authors Chodidjah Chodidjah Mohammad Dhanny Akbar Naufal Aditya Ramadhan Vito Mahendra