Biodiversitas Journal of Biological Diversity
Vol. 7 No. 3 (2006)

Concentration of TNF-α in the peritoneal fluid and serum of endometriotic patients

TEDJA DANUDJA OEPOMO (Fakultas Kedokteran, Universitas Sebelas Maret (UNS) Surakarta 57126. Bagian/KSMF Obstetri dan Ginekologi, Rumah Sakit Umum Daerah (RSUD) dr. Muwardi Surakarta 57126.)



Article Info

Publish Date
26 Apr 2006

Abstract

The aim of this research was to expose the relation between tumor necrosis factor alpha (TNF-α) in the peritoneal fluid and in the serum of endometriosis patients. It was conducted at Dr. Muwardi Hospital Surakarta. Twenty patients undergoing laparoscopic operation because of endometriosis indication (Endometriosis Group), 20 women (aged 23 to 40) who undergo interval sterilization by means of laparoscopic technique. During laparoscopic operation, peritoneal fluid is taken to examine TNF-α by ELISA technique. At the same time, the serum isalso taken to examine TNF-α by the same technique. The research result indicated that by independent sample t-test, the TNF-α concentration in the Endometriosis Group is quite different from the control group (P=0.00). The simple linear regression test shows a strong positive one-way correlative relation between TNF-α concentration in the peritoneal fluid and TNF-α concentration in the serum in the Endometriosis Group. The research result indicated that the TNF-α concentration in the serum can be used as a reflection of endometriosis. A statistical test is done to find the limit value based on sensitivity and specification.© 2006 Jurusan Biologi FMIPA UNS SurakartaKey words: endometriosis, TNF-α, peritoneal fluid, serum.

Copyrights © 2006






Journal Info

Abbrev

biodiv

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology

Description

The Biodiversitas Journal was first published in 2000 by the Department of Biology, FMNS, Universitas Sebelas Maret, Surakarta, Indonesia, then in 2006 it was co-published by the Society for Indonesian Biodiversity and that department; since 2017 it was also hosted by Smujo. From 2003-2012 it was ...