Biodiversitas Journal of Biological Diversity
Vol. 18 No. 1 (2017)

The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents

YANIETA ARBIASTUTIE (Doctoral Program of Forestry Science, Faculty of Forestry, Universitas Gadjah Mada. Jl. Agro No. 1 Bulaksumur, Sleman 55281, Yogyakarta, Indonesia.)
DJOKO MARSONO (Faculty of Forestry, Universitas TaFaculty of Forestry, Universitas Gadjah Mada. Jl. Agro No. 1, Bulaksumur, Sleman 55281, Yogyakarta, Indonesia njungpura. Jl. Daya Nasional Pontianak, West Kalimantan, Indonesia)
MAE SRI HARTATI (Faculty of Medicine, Universitas Gadjah Mada. Jl. Farmako, Sekip Utara, Sleman 55281, Yogyakarta, Indonesia)
RISHADI PURWANTO (Faculty of Forestry, Universitas Gadjah Mada. Jl. Agro No. 1, Bulaksumur, Sleman 55281, Yogyakarta, Indonesia)



Article Info

Publish Date
13 Feb 2017

Abstract

Abstract. Arbiastutie Y, Marsono Dj, Hartati MS, Purwanto R. 2017. The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents. Biodiversitas 18: 109-115. This study aims to screening 97 species obtained from the understorey plants of The Gunung Gede Pangrango National Park of West Java, Indonesia as the anticancer cervixs agents. The anticancer plant activity is determined by the cytotoxicity assay of understorey plant methanol extracts against HeLa cervixs cancer cells using MTT test method. IC50 which is an indicator of cytotoxicity is determined by the probit analysis. The results show that of the 97 plants tested, there are five potential anticancer plants i.e. Physalis peruvianaL. (Solanaceae), Tithonia diversifolia (Hemsl.) A. Gray (Asteraceae), Lantana camara L. (Verbenaceae), Clidema hirta (L). D.Don (Lamiaceae), and Solanum torvum Sw (Solananceae) with IC50 values of 67.85 µg/mL, 3.38 µg/mL, 43.54 µg/mL, 36.93 µg/mL, and 59.09 µg/mL respectively. The phytochemical compound find five understorey plants consisting of alkaloids, steroids, terpenoids, phenol, flavonoids and tannin. Keywords: Anticancer, Gunung Gede Pangrango National Park, HeLa, MTT assay, understorey plant

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Journal Info

Abbrev

biodiv

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology

Description

The Biodiversitas Journal was first published in 2000 by the Department of Biology, FMNS, Universitas Sebelas Maret, Surakarta, Indonesia, then in 2006 it was co-published by the Society for Indonesian Biodiversity and that department; since 2017 it was also hosted by Smujo. From 2003-2012 it was ...