Biodiversitas Journal of Biological Diversity
Vol. 22 No. 4 (2021)

Agronomic characteristics of 30 promising lines of aromatic, red, and black rice and their antioxidant and cytotoxic effects in some cancer cells

YUSUF LIMBONGAN (1Faculty of Agriculture, Universitas Kristen Indonesia Toraja. Jl. Jenderal Sudirman No. 9, Bombongan, Makale, Tana Toraja 91811, South Sulawesi, Indonesia)
RICO RAMADHAN (Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga. Jl. Dr. Ir. H. Soekarno, Mulyorejo, Surabaya 60115, East Java, Indonesia)
KUNIYOSHI SHIMIZU (Faculty of Agriculture, Kyushu University. 744 Motooka, Nishi-ku, Fukuoka, 819-0395, Japan)
Enos Tangkearung (Faculty of Forestry, Universitas Mulawarman. Jl. Penajam, Gunung Kelua, Samarinda 75123, East Kalimantan, Indonesia)



Article Info

Publish Date
11 Mar 2021

Abstract

Abstract. Limbongan Y, Ramadhan R, Shimizu K, Arung ET. 2021. Agronomic characteristics of 30 promising lines of aromatic, red, and black rice and their antioxidant and cytotoxic effects in some cancer cells. Biodiversitas 22: 1695-1700. In our effort to increase rice production, some activities were done such as increased land production, rice planting patterns, and crossbreeding some rice with the special characteristic. We have cross-bred aromatic rice with red rice and black rice. These activities resulted in thirty lines of rice varieties. The thirty lines of rice variation were extracted with ethanol and evaluated the extracts for their phytochemicals, antioxidant activity, and cytotoxicity effect on cancer cell lines (MCF-7, HeLa, and OVK-18). The phytochemicals of thirty lines variation of rice showed variation in their contents. The line of F2BA201 extracts showed the strongest in antioxidant with IC50 2.43 ?g/mL while Vitamin C was 32.93 ?g/mL. The line of F2LD20 extracts displayed potent inhibition with value of 40.2% against OVK-18 cancer cells while 5FU as positive control revealed percentage inhibition with value of 21.2%. Based on the results, the thirty line rice variations exhibited antioxidant and anti-cancer potential.

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Journal Info

Abbrev

biodiv

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology

Description

The Biodiversitas Journal was first published in 2000 by the Department of Biology, FMNS, Universitas Sebelas Maret, Surakarta, Indonesia, then in 2006 it was co-published by the Society for Indonesian Biodiversity and that department; since 2017 it was also hosted by Smujo. From 2003-2012 it was ...