Joseph
Vol 4 No 1 (2024): Journal of Science and Pharmacy (Joseph)

UJI STABILITAS FISIK SEDIAAN SERUM WAJAH EKSTRAK DAUN BELIMBING MANIS (Averrhoa carambola L.) DENGAN VARIASI KONSENTRASI PROPILEN GLIKOL SEBAGAI HUMEKTAN

Devi Kurnia Saputri (universitas An Nuur)
Gigih Kenanga Sari (universitas An Nuur)
Estuningtyas Ayu Hapsari (universitas An Nuur)



Article Info

Publish Date
20 Dec 2024

Abstract

Background: Sweet star fruit leaf (Averrhoa carambola L.) is a plant that contains antibacterial compounds such as alkaloids, flavonoids, saponins, tannins and triterpenoids that are used as acne therapy. Several product dosage forms have been developed for serum, one of which is in form slightly viscous. Humectants serve to improve the stability of the material over long period of time. Purpose: This research was conducted to find out at what oncentration propylene glycol as a humectant meets the physical stability test of a good serum preparations. Method: Sweet star fruit leaf (Averrhoa carambola L.) was extracted using the maceration method using methanol. The serum preparation consists of 3 formula with different concentrations of propylene glycol, namely formula I 15%, formula II 20% and formula III 25%. Evaluation of physical stability was carried out with 12 days in an accelerated test (Cycling test) with organoleptic testing parameters, homogeneity, pH, viscosity, adhesion and spreadability. Results: Serum preparations of weet star fruit leaf extract (Averrhoa carambola L.) in formula I, formula II and formula III have physical characteristics and stability that comply with SNI standards. Conclusion: The concentration of propylene glycol 25% in formula III shows the most stable serum stability properties compared to formula I and formula II  

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Journal Info

Abbrev

unan

Publisher

Subject

Description

Joseph: Journal of Science and Pharmacy merupakan jurnal ilmiah yang diterbitkan oleh Universitas An Nuur sebagai media publikasi dan diseminasi hasil penelitian di bidang ilmu pengetahuan alam dan farmasi. Jurnal ini bertujuan untuk mendorong kemajuan ilmu pengetahuan melalui penyebaran informasi ...