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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Nusantara Hasana Journal JPKM Cahaya Negeriku Jurnal Farmasi Ikifa Joseph THE SHINE CAHAYA DUNIA S-1 KEPERAWATAN
Gigih Kenanga Sari
Universitas An Nuur
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Education Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Other

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IDENTIFIKASI SENYAWA ALKALOID EKSTRAK ETANOL 70% DAUN BELIMBING MANIS (Averhoa carambola L.) SECARA KROMATOGRAFI LAPIS TIPIS DENGAN ELUEN N-HEKSAN DAN ETIL ASETAT Gigih Kenanga Sari; Nazdia Putri Nur Afiana
Jurnal Farmasi IKIFA Vol. 3 No. 2 (2024): JURNAL FARMASI IKIFA VOL.3 NO.2 JULI TAHUN 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

This research aims to identify alkaloid compounds from 70% ethanol extract of sweet starfruit leaves (Averhoa carambola L.) originating from Tarub Village, Tawangharjo District, Grobogan Regency. The identification method is laboratory observation using Thin Layer Chromatography (TLC) using the eluent N-hexane and ethyl acetate ratio (7:3). The selection of N-hexane and ethyl acetate eluents based on different polarities aims to obtain the best solvent, which can have an influence on the chemical content produced. The solvent was also able to influence the yield of the resulting compound. The TLC results with N-hexane eluent showed an orange red color and an Rf value of 0.8. And the TLC results with ethyl acetate eluent showed a pink color with an Rf value of 0.2. Conclusion: 70% ethanol extract of sweet star fruit leaves positively contains alkaloid compounds.
FORMULASI DAN UJI MUTU FISIK SEDIAAN PERMEN JELLY FRAKSI ETIL ASETAT BUAH KEMUKUS (Piper cubeba L.f) Amanda Risky Damayanti; Gigih Kenanga Sari; Wahyu Purwanjani
Jurnal Farmasi IKIFA Vol. 3 No. 3 (2024): JURNAL FARMASI IKIFA VOL.3 NO.2 OKTOBER TAHUN 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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The ethyl acetate fraction of cubeb fruit (Piper cubeba L.f) contains alkaloid, flavonoid and terpenoid compounds that function to improve memory. Jelly candy is currently popular and is one of the favorite foods in various circles, because it has a chewy characteristic, therefore a new innovation was made in developing cubeb fruit. This study aims to determine the physical quality of the ethyl acetate fraction of cubeb fruit jelly candy preparation. The physical quality test consists of organoleptic color, scent and texture, water content, ash content, reducing sugar, pH, and weight uniformity. The formulation of the jelly candy preparation uses ethyl acetate fraction and is divided into 3 formulations with the concentrations used, namely 0.488g, 0.977g, 1.955g. The results of physical quality tests of FI, FII and FIII jelly candy preparations meet the requirements according to SNI standards including: organoleptic tests of color, aroma and texture, water content, ash content, reducing sugar, pH, and weight uniformity. The ethyl acetate fraction of cubeb fruit has alkaloid, flavonoid, and terpenoid compounds. The ethyl acetate fraction of cubeb fruit can be formulated into jelly candy preparations, all formulations have good physical quality according to SNI standards and formulation I is the best formulation.
OPTIMASI FORMULASI SABUN PEMBERSIH WAJAH ANTIBAKTERI VARIASI KOMBINASI MINYAK ATSIRI KULIT JERUK DAN EKSTRAK DAUN KEMANGI Gigih Kenanga Sari; Estuningtyas Ayu Hapsari
Jurnal Farmasi IKIFA Vol. 3 No. 3 (2024): JURNAL FARMASI IKIFA VOL.3 NO.2 OKTOBER TAHUN 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Background: orange peel essential oil and basil leaf extract are known as natural ingredients that contain medicinal ingredients. The extracts of these two plants are useful as antibacterials. Objective: to determine the antibacterial activity of facial soap containing the active ingredients orange peel essential oil and basil leaf extract. The methods studied include: organoleptic properties, pH value, foam height, free alkali content, specific gravity and antibacterial activity. The type of research used is experimental research. Data collection was carried out by measuring, while data analysis was descriptive and analytical. The research design used was a post-test only control design. Conclusions include the preparation of facial cleansing soap with a combination of orange peel essential oil and basil leaf extract which meets SNI requirements which is classified as an inhibitory bacterial work zone but the most optimal is F3, there are differences in the diameter of the inhibitory zone for the growth of Staphylococcus aureus bacteria in facial cleansing soap with a combination of active ingredients. orange peel essential oil and basil leaf extract.
Gerakan Anak Sehat: Sosialisasi Peran Multivitamin dalam Menjaga Kesehatan Siswa SD Negeri 1 Curut Gigih Kenanga Sari; Novia Julianti; Rara Erika; Sindy Mellyana Putri
Jurnal Pengabdian kepada Masyarakat Cahaya Negeriku Vol 6 No 01 (2026): Jurnal Pengabdian kepada Masyarakat Cahaya Negeriku
Publisher : LPPM AN Nuur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35720/jpkm.v6i01.83

Abstract

Background: Multivitamins are pharmaceutical preparations consisting of vitamins, either in single or combined forms, that serve to meet the nutritional needs of the body. Vitamins are essential for the human body as they play a role in metabolism, immunity, and other physiological functions. However, the human body cannot produce sufficient amounts of vitamins, making dietary intake or supplementation necessary. Objective: To enhance students' understanding of the importance of consuming multivitamins to maintain their health and prevent diseases. Method: This activity involved a socialization program conducted at SDN 1 Curut on Tuesday, December 3, with the participation of 13 students. The program included presentations and discussions focusing on the importance of consuming multivitamins. Results: The socialization activity at SDN 1 Curut, involving 13 fourth-grade students, ran smoothly and received positive feedback. Students' understanding of the importance of consuming multivitamins improved significantly after attending the session and participating in the posttest. The activity also received good appreciation from the participants. Conclusion: The socialization regarding the importance of consuming multivitamins successfully enhanced the understanding of the fourth-grade students at SDN 1 Curut. The majority of the students demonstrated high enthusiasm and better comprehension of the benefits of multivitamins in maintaining body health.
Formulasi Permen Jelly dari Infusa Lengkuas Putih (Alpinia galanga (L.)) Sebagai Suplemen Peningkat Daya Ingat Gigih Kenanga Sari; Bentar Jatmiko; Ning Febriani
Jurnal Penelitian Pendidikan IPA Vol 12 No 4 (2026)
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i4.14320

Abstract

Background: White galangal (Alpinia galanga L.) is a herbal plant containing bioactive compounds with potential to support cognitive function, making it a promising candidate for functional food development. Objective: This study aimed to formulate white galangal infusion into a jelly candy dosage form and to evaluate its physical quality. Methods: White galangal rhizomes were dried at 40 °C, processed into simplisia powder, and extracted using the infusion method. The obtained infusion was characterized through phytochemical screening and thin-layer chromatography, then formulated into jelly candies in three formulations with varying infusion concentrations. Physical quality evaluation included organoleptic properties, texture, moisture content, ash content, reducing sugar, pH, and weight uniformity. Results: The results showed that the white galangal infusion contained flavonoids, phenolics, terpenoids, and quinones. All jelly candy formulations met the required physical quality standards, with variations in color, aroma, moisture content, and pH influenced by infusion concentration but remaining within acceptable limits. Conclusion: White galangal infusion jelly candy has the potential to be developed as a herbal-based functional food product.
UJI STABILITAS FISIK SEDIAAN FACE SPRAY EKSTRAK ETANOL 96% BIJI BUAH ALPUKAT (Persea Americana Mill) DENGAN VARIASI KONSENTRASI GLISERIN Anisa Eka Pafitri; Gigih Kenanga Sari; Wahyu Purwanjani
Nusantara Hasana Journal Vol. 6 No. 1 (2026): Nusantara Hasana Journal, June 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v6i1.2195

Abstract

Avocado seeds contain secondary metabolite compounds in the form of alkaloids, flavonoids, saponins, tannins, triterpenoids and steroids. To moisturize and protect the face, spray face spray. The natural ingredients of avocado seeds can be used as a face spray because they contain antioxidants. This study aimed to analyze physical stability of Persea Americana seed extract face spray preparation against variations in glycerin concentration carried out for 6 cycles. In this research, avocado seed extract was obtained using the maceration method and formulated into a face spray preparation with varying glycerin concentrations of 20%, 25% and 30%. The physical stability test of avocado seed extract was carried out using the cycling test method for 6 cycles. P. americana seed extract could be formulated as a face spray. Variations in glycerin concentration affected the results of stability tests on face spray preparations of P. americana seed extract. The F3 formulation had the best results in the face spray preparation of avocado seed extract. Avocado seed extract could be formulated in a face spray with a concentration of 30% to give the best results
PHYSICAL STABILITY TEST FORMULA ON SOYBEAN SEEDS EXTRACT (GLYCINR MAX L.) GROBOGAN REGENCY IN GEL Gigih Kenanga Sari; Anita Dwi Septiarini; Katharina Anrina
Joseph: Journal of Science and Pharmacy Vol 1 No 1 (2021): Journal of Science and Pharmacy (Joseph)
Publisher : Universitas An Nuur

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Abstract

Background: Soybean (Glycine max L.) is one of the leading food commodities in Grobogan Regency. Soybean belongs to the   flavonoid group, which is one of the natural antioxidant-producing   foodstuffs. One of the important components / bioactive compounds   found in soybeans and acts as an antioxidant is isoflavones.   Isoflavones contained in soybean extract are non-toxic to human   skin and can provide a protective effect from the sun, so it can be   said that the isoflavones contained in soybean extract can have the   ability to scavenge free radicals as well as act as a skin protector   from the sun. To obtain a protective effect against ultraviolet light,   an appropriate dosage form should be selected, which does not   cause irritation, and can carry medicinal ingredients well. Gel   preparations have several advantages including non-sticky, easy to   dry, has a thin film layer so that it is easy to wash. Purpose: This   study was to produce a gel preparation and to determine the physical stability of the Soybean (Glycine max L.) Seed Extract Formulation in Grobogan Regency in Gel Preparations. Method: The instrument uses analytical balance, measuring cup, object glass, stirring rod, mortar and stamper, pH stick, viscometer, stopwatch, adhesion test equipment, dispersion test equipment, and freeze dry. The ingredients are Grobogan soybean seed dry extract, HPMC, methylparaben, propylparaben, glycerin, and distilled water. Results: This research resulted in a gel preparation with soybean seed extract as the raw material. The gel produced when the concentration of HPMC was doubled, from a concentration of 5% to 10% and from a concentration of 10% to 20% could increase viscosity, stickiness, and decrease dispersion, but the increase in HPMC concentration did not affect the pH of the preparation. Conclusion: This study resulted in a gel preparation with an increase in concentration and the gel can affect the physical stability of the gel as indicated by the increase in viscosity, gel adhesion, and a decrease in gel dispersion, but the increase in HPMC concentration did not affect the pH of the preparation
ANTIBACTERIAL ACTIVITY TESTING OF COLLASE LEAF EXTRACT (Centella asiatica L.) AGAINST Propionibacterium acnes BACTERIA Bentar Jatmiko; Gigih Kenanga Sari; Mingle A Pistanty
Joseph: Journal of Science and Pharmacy Vol 2 No 1 (2022): Journal of Science and Pharmacy (Joseph)
Publisher : Universitas An Nuur

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Abstract

Background: Propionibacterium acnes or P.acnes is a normal skin flora bacteria, but can be the cause of opportunistic infections in the form of acne. Generally, acne is treated using antibacterials aimed at reducing the colonization of bacteria. The centtella asiatica plant (Centtella asiatica) is a plant of one genus as Centella. Research shows that leaf ethanol extract (Centtella asiatica) has antibacterial activity. Purpose: This study aims to determine the antibattery activity of Centella asiatica leaf extract against Propionibacterium acnes and adequate concentration in inhibiting the growth of Propionibacterium acnes. Method: Centella asiatica leaves (Centella asiatica) were extracted by maceration method using 70% ethanol solvent. The dieprolwh extract was carried out phytochemical tests and antibacterial activity tests with the well method against Propionibacterium acnes. Clindamycin positive control 20μg, DMSO negative control 10%. Results: Phytochemical test of ethanol extract of centella asiatica leaves containing:
UJI AKTIVITAS GEL EKSTRAK DAUN KELOR (Maringa oelifera L.) DARI KABUPATEN BLORA TERHADAP PENYEMBUHAN LUKA BAKAR PADA KELINCI New Zealand Dina Permata Sari; Gigih Kenanga Sari; Maulita Saraswati
Joseph: Journal of Science and Pharmacy Vol 2 No 1 (2022): Journal of Science and Pharmacy (Joseph)
Publisher : Universitas An Nuur

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Abstract

Background: The saponin and tannin compounds in Moringa leaf extract stimulate the formation of collagen, namely in the wound healing process and in cleaning so that it is more effective in healing burns. Purpose: The purpose of this study was to determine the effect of Moringa leaf (Moringa oleifera L.) ethanol extract gel on burn healing Method: This study aims to determine the effectiveness of Moringa leaf extract gel in healing burns in rabbits. This study used 70% ethanol and divided into 3 formulas with the same extract concentration of 9%, for positive control (Biopacenton), negative control (Extract). Results: Data analysis was carried out using one way Anova. The results showed that the ethanol extract gel of Moringa leaves (Moringa oleifera L.) with a concentration of 9% with HPMC bases of 8%, 9% and 10% , had activity on the healing of burns on the backs of New Zealand strain rabbits. Conclusion: Moringa leaf ethanol extract gel (Moringa oleifera L.) can heal burns on the backs of New Zealand rabbits.
FORMULASI GEL HAND SANITIZER EKSTRAK DAUN PEGAGAN (Centella asiatica) DAN AKTIVITASNYA TERHADAPStaphylococcus aureus Maulita Saraswati; Gigih Kenanga Sari; Wahyu Purwanjani
Joseph: Journal of Science and Pharmacy Vol 2 No 1 (2022): Journal of Science and Pharmacy (Joseph)
Publisher : Universitas An Nuur

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Abstract

 Background: Indonesia is a tropical country that has very abundant biodiversity and has various potentials for health. One of these biodiversities is pegagan leaves (Centella asiatica). Pegagan (Centella asiatica) is one of the plants that contains antibacterial substances, including flavonoids, saponins, tannins, phenols and steroids. Prevention of the spread of bacteria can be done by washing hands with soap and clean running water. Along with the development of science and technology, cleaning hands does not have to use water and soap but can use antiseptic hand gel (hand sanitizer)   to kill microorganisms on the surface of the skin. Purpose: to determine whether the gotu kola leaf extract hand sanitizer gel preparation has antibacterial activity against Staphylococcus aureus Method: Extraction by maceration of pegagan leaf extract (Centella asiatica) using 96% ethanol solvent. After obtaining a thick extract, then enter it into the formulation to make a hand sanitizer gel preparation which is then tested on Staphylococcus aureus bacteria using the disc diffusion method. Results: The results of this study showed that the hand sanitizer gel with pegagan extract (Centella asiatica) showed an inhibitory effect on bacterial growth with an inhibitory value of 15.4 mm in formulation 3 with a pegagan extract concentration of 60%. Conclusion: Hand sanitizer gel from pegagan extract (Centella asiatica) has antibacterial activity against Staphylococcus aureus 
Co-Authors Amanda Risky Damayanti Anisa Eka Pafitri Anita Dwi Septiarini Anita Lufianti Bentar Jatmiko Bentar Jatmiko Devi Kurnia Saputri Dhanisa Dwi Nugrahanti Dina Permata Sari Ella Laela Musyarofah Estuningtyas Ayu Hapsari Indriani Dini Mustava Katharina Anrina Maulita Saraswati Mingle A Pistanty Nazdia Putri Nur Afiana Ning Febriani Novia Julianti Rara Erika Rumanis Afifah Sindy Mellyana Putri Siti Zulifat Supriyanto sutiyono Wahyu Purwanjani Yulia Rika Femina