<![CDATA[Background: Although several assessment instruments are available for patients with cancer, most focus primarily on physical symptoms and do not comprehensively assess patients' physical, psychological, social, and spiritual needs. Objective: This study aimed to develop a multidimensional assessment instrument for patients with cancer and evaluate its content validity. Method: An instrument development study was conducted through literature review, item synthesis, and a two-round Delphi process involving 12 multidisciplinary experts. An initial 37-item instrument covering physical, psychological, social, and spiritual domains was developed. Content validity and expert consensus were evaluated using the Item-level Content Validity Index (I-CVI) and interquartile range (IQR). Results: Of the initial 37 items, 35 were retained following two Delphi rounds. Fifteen items were revised to improve clarity and conceptual alignment, whereas two psychological items were removed because of insufficient content validity and conceptual inconsistency. The final instrument comprised 35 items representing four multidimensional domains, with acceptable expert consensus across all retained items. Conclusion: The developed 35-item multidimensional assessment instrument demonstrated satisfactory content validity and expert consensus. It provides a preliminary framework for comprehensively assessing the multidimensional needs of patients with cancer and supports further psychometric evaluation before clinical implementation.]]>
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