Journal of Clinical Microbiology and Infectious Diseases
Vol. 6 No. 1 (2026): Available online : 1 June 2026

Profile of Candida species urinary tract infection amongst intensive care unit patients at a teaching hospital in Yogyakarta, Indonesia

Vyonne Chiara Sentosa (Medicine Study Program, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Indonesia)
Raden Ludhang Pradipta Rizki (Department of Clinical Microbiology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Indonesia)
Nurrokhman (Department of Clinical Microbiology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Indonesia)
Marselinus Edwin Widyanto Daniwijaya (Department of Clinical Microbiology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Indonesia
Universitas Gadjah Mada Academic Hospital, Indonesia)



Article Info

Publish Date
25 May 2026

Abstract

Introduction: Candida species have been reported to be the most common fungal causative agents of urinary tract infections (UTI) in the intensive care unit (ICU), causing up to 20 - 25% of UTIs. This study aims to create profiles of patients with Candida spp. UTI, antifungal administration, Candida species accounting for UTI, and mortality rate in the ICU of a teaching hospital in Yogyakarta, Indonesia. Methods: This study was a retrospective, cross-sectional, descriptive analysis using electronic health records from ICU patients of a teaching hospital in Yogyakarta, Indonesia, with positive Candida species urine culture from January 2020 to December 2023. Result: 46 women (57.5%) and 34 men (42.5%) had positive Candida urine cultures, with the majority in the age group ≥ 60 years old (63.75%) and with prior cardiovascular disorders (17.5%). Correlation established between >7 days of ICU stay and Candida species UTI, occurring in 64 patients (80%). The majority of ICU patients with Candida species UTI received invasive procedures (60%). 77 patients (96.25%) had a primary diagnosis of non-HAIs. 35 Candida tropicalis isolates (43.75%), 31 Candida albicans isolates (38.75%), 4 Candida glabrata isolates (5%), and 3 Candida parapsilosis isolates (3.75%) were found in urine cultures of ICU patients. Fluconazole (83.75%) was identified as the most frequent antifungal administered. A mortality rate of 48.75% was demonstrated in ICU patients with Candida species UTI. Conclusions: Prevalence of Candida species UTI in ICU patients of a teaching hospital in Yogyakarta, Indonesia, increases when patients are females, ≥60 years old, have prior disease and complications of cardiovascular disease, stay >7 days in the ICU, use urinary catheters, and have a primary diagnosis of non-HAIs. Fluconazole is the most frequent antifungal administered. Candida tropicalis was identified as the most frequent causative agent of UTI in ICU patients with a mortality rate of 48.75%.

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Journal Info

Abbrev

JCMID

Publisher

Subject

Immunology & microbiology

Description

Journal of Clinical Microbiology and Infectious Diseases; peer-reviewed journal aiming to communicate high-quality research articles, reviews, and general articles in the field. JCMID publishes articles that encompass basic research/clinical studies related to microbiology and infectious disease. ...