<![CDATA[Measles remains a public health concern in Indonesia, including Jakarta, contributing to the country’s disease burden. Sustained transmission during 2022-2024, despite reported vaccination coverage above 90%, suggests the presence of vulnerable groups. This study aimed to describe patterns and identify factors associated with laboratory-confirmed measles in Jakarta during 2022-2024. A cross-sectional study was conducted using routine surveillance data from all individuals reported as suspected measles cases during the study period. Descriptive analysis summarizes the distribution, while multivariable analysis identifies associated factors. Of the 4,194 suspected cases of measles, 22.8% were laboratory-confirmed positive. Showed a fluctuating temporal pattern, increasing from 20.6 % in 2022 to 42% in 2023, followed by a sharp decline to 3.5% in 2024. Among reported suspected measles cases, children aged ≤ 5 years had higher odds of laboratory-confirmed measles than those aged >5 years (aPOR 1.38; 95% CI 1.17-1.63). Unvaccinated individuals had a higher odds of laboratory-confirmed measles than fully vaccinated individuals (aPOR 2.53; 95% CI 2.09-3.06). Sex and travel history were not associated. Measles transmission in Jakarta persisted with a fluctuating pattern and was associated with children aged 5 and younger and unvaccinated individuals. Strengthening routine measles immunization and prioritizing susceptible groups identified through surveillance data are needed. Keywords: Measles, Surveillance, Risk Factors, Vaccine-Preventable Disease]]>
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