The development of Student Worksheets (LKPD) with an ethnoscience approach is one of the important strategies to realize contextual science learning, rooted in local wisdom, as well as relevant to the demands of 21st century skills. This study uses the Systematic Literature Review (SLR) method with PRISMA guidance to identify, select, and analyze publications on the development of ethnoscience LKPD in the 2015–2025 period that are indexed in the Scopus database and other supporting sources. From the initial 210 documents, the gradual selection process produced 12 articles that met the inclusion criteria related to research design, openness of access, and relevance of themes to the development of ethnoscience LKPD. The results of the study show that the research is dominated by research and development (R&D) design with the ADDIE model or similar, focusing on testing the validity, practicality, and effectiveness of LKPD in improving learning outcomes, science literacy, motivation, and students' appreciation of local culture. Overall, the development of LKPD with an ethnoscience approach is proving to be a relevant and prospective topic to be researched, with opportunities for further development on a variety of contexts, educational levels, and integration with innovative approaches such as STEM, project-based learning, and the use of digital technology.
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