This research aims to find out and analyze division of labor, work ethic and supervision simultaneously and partially has a significant effect on Performance employees at Anutapura Palu Hospital. As for the results of the research, the division of labor has a regression coefficient of 0.546 with a significance value of 0.002, which shows that effective division of labor can improve employee performance at Anutapura Palu Hospital. Work ethic was also proven to have a positive effect on employee performance, with a regression coefficient of 0.460 and a significance value of 0.049. Effective supervision also has a significant influence on employee performance, with a regression coefficient of 0.394 and a significance value of 0.003. The R-Square value of 0.877 indicates that 87.7% of the variation in employee performance can be explained by the variables of division of labor, work ethic, and supervision. Thus, these variables have a great contribution in determining the performance of employees at Anutapura Palu Hospital.
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