Jambura Journal of Mathematics
Vol 8, No 2: August 2025

Mathematical Modeling and Parameter Estimation of Meningitis Transmission Dynamic using Vaccination Strategies in Indonesia

Aufa Al Musyarof (Institut Teknologi Sepuluh Nopember)
Faris Nur Hibban (Institut Teknologi Sepuluh Nopember)
Mardlijah Mardlijah (Institut Teknologi Sepuluh Nopember)
Didik Khusnul Arif (Institut Teknologi Sepuluh Nopember)



Article Info

Publish Date
16 Aug 2026

Abstract

Meningitis is a public health threat because it progresses rapidly and has serious clinical impacts, including long-term disability. This research develops a six-compartment mathematical model to examine the dynamics of meningitis transmission by dividing the population into susceptible, exposed, infected, recovered without disability, recovered with disability, and vaccinated groups. The model parameters were fitted using the least squares method based on annual meningitis case data in Indonesia from 1990 to 2023 according to estimates originating from the Institute for Health Metrics and Evaluation (IHME)/Global Burden of Disease, accessed through the archived Our World in Data source. Model validation shows high accuracy performance, with a Mean Absolute Percentage Error value of 3.12%. Local sensitivity analysis indicates that the transmission rate (\beta) and vaccination rate (\xi) are the parameters most influencing changes in R0 resulting from parameter variation. Numerical simulation results show that rapid immunization at the onset of an outbreak is the most effective strategy among the vaccination scenarios examined to expedite herd immunity and limit disease spread.

Copyrights © 2025






Journal Info

Abbrev

jjom

Publisher

Subject

Mathematics

Description

Jambura Journal of Mathematics (JJoM) is a peer-reviewed journal published by Department of Mathematics, State University of Gorontalo. This journal is available in print and online and highly respects the publication ethic and avoids any type of plagiarism. JJoM is intended as a communication forum ...