Genetic literacy is an essential component of scientific literacy that enables students to understand genetic concepts and make evidence-based decisions. However, the level of genetic literacy among Indonesian high school students remains relatively low, particularly in the topic of heredity patterns, which is often taught theoretically and lacks connections to real-world issues. This study aimed to develop a Student Worksheet (LKPD) based on contextual issues in heredity patterns to strengthen the genetic literacy of senior high school students. The study employed a Research and Development (R&D) method using the ADDIE model, implemented up to the development stage. The product was validated by subject matter experts and media experts and subsequently tested through limited trials involving 10 Biology Education students and 43 senior high school students. Data were analyzed descriptively using a Likert scale. The results showed that the developed LKPD achieved a media expert validation score of 3.8 and a subject matter expert validation score of 3.9, both categorized as highly valid. The limited trial results obtained an average score of 3.6, categorized as very good. Overall, the contextual issue-based LKPD achieved an average quality score of 3.7, categorized as very good, indicating that it is suitable for use as a learning resource to support genetics instruction in senior high schools.
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