<![CDATA[This study aims to develop a valid, practical, and effective Socio-Scientific Issues (SSI)-based e-module on reproductive system material to improve critical thinking skills of eleventh-grade high school students. The research method used is Research and Development (R&D) with a 4D development model (Define, Design, Develop, Disseminate). The limited trial subjects in this study involved 15 eleventh-grade students of SMA SHAFTA Surabaya. Data collection instruments included an observation sheet for learning implementation and a critical thinking ability test use pre-test and post-test. The results showed that the e-module was declared practical based on the percentage of learning implementation of 96% with a very good category and was declared effective based on the increase in students' critical thinking skills with an average N-gain score of 0.83 with a high category. Based on these results, it can be concluded that the SSI-based e-module on reproductive system material is suitable for use as a learning medium to train students' critical thinking skills.]]>
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