This study aimed to develop an E-Booklet learning media on the human excretory system that is valid, practical, and effective in improving the learning outcomes of Grade XI IPA 6 students at SMA Negeri 8 Medan. This research employed the Research and Development (R&D) method using the ADDIE development model, which consists of five stages: Analysis, Design, Development, Implementation, and Evaluation. The research instruments included expert validation sheets, teacher and student response questionnaires, as well as learning achievement tests (pretest and posttest). The results showed that the developed E-Booklet learning media was categorized as highly valid, with validation scores of 92.3% from the design expert and 89.6% from the subject matter expert. The media was also categorized as highly practical, as indicated by the teacher response score of 92.66% and the student response score of 87.06%. Furthermore, the effectiveness of the media was demonstrated by an N-Gain score of 0.71, which falls into the high category, and an N-Gain percentage of 71.86%, which is categorized as highly effective. Therefore, the E-Booklet learning media on the human excretory system is considered valid, practical, and highly effective, making it suitable for improving students' learning outcomes.
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