Potential of Moringa oleifera as an Antibacterial and Antibiofilms in Root Canal & Tooth Surface Disease Empirical, In Vitro & In Silico

Meiny Faudah Amin (Dental Conservation, Faculty of Dentistry, Universitas Trisakti, Jakarta, Indonesia)
Taufiq Ariwibowo (Dental Conservation, Faculty of Dentistry, Universitas Trisakti, Jakarta, Indonesia)
Salsabila Aqila Putri (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, West Java, Indonesia)
Dikdik Kurnia (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, West Java, Indonesia)

SDJ
VOLUME 8, ISSUE 1, JANUARY 2024

Moringa oleifera is one of the typical plant in Southeast Asia, especially Indonesia. Moringa leaves are known as plants containing bioactive compounds with multiple activities. Polyphenol, quercetin, tannin, and saponin compounds in Moringa leaves have anti-inflammatory, antidiabetic, and antibacterial activities. The potential of Moringa leaf extracts as an antibacterial need to be tested in silico and in vitro to determine the suitability of specific bioactive compounds. The aim is to know the potential of Moringa oleifera leaves as antibacterial, antibiofilm in root canal disease and tooth surfaces. This research method is an empirical study, In vitro and In silico.