<![CDATA[Work stress is a physical and emotional response that can occur when job demands do not align with a worker's capabilities, resources, or needs. Nurses are a group of healthcare professionals at risk of experiencing work stress due to the high demands and workloads involved in providing healthcare services. This study aimed to identify factors associated with work stress among nurses in the Emergency Department (ED) and inpatient wards of Tenriawaru Bone Regional General Hospital (RSUD). This was a quantitative study utilizing a cross-sectional design. The study population consisted of 60 nurses: 30 from the ED and 30 from the inpatient wards. The entire population was included in the sample using a total sampling technique, resulting in 60 respondents. Data were collected via questionnaires and analyzed using the chi-square test with a significance level of α=0.05. The results showed a significant association between age and work stress (p=0.001) and between workload and work stress (p<0.001). Meanwhile, length of service was not significantly associated with work stress (p=0.061). It can be concluded that age and workload are factors associated with work stress among nurses in the ED and inpatient wards of Tenriawaru Bone RSUD. Therefore, workload management aligned with nurses' capabilities and capacities, along with the implementation of stress management strategies, is necessary to reduce the risk of work stress.]]>
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