Background: The prevalence of sexually transmitted infections (STIs) in adolescents is on the rise annually. Various initiatives have been implemented to mitigate morbidity and mortality rates. However, the incidence of STIs among adolescents remains alarmingly high, highlighting the need to strengthen preventive measures and expand access to high-quality screening services. Objective: To identify and categorize strategies for improving prevention and screening behaviors relate to STIs among adolescents. Method: The investigation employed a comprehensive review design. Articles were procured from four databases: PubMed, ProQuest, ScienceDirect, and Web of Science. All articles were evaluated for their suitability to address the research questions using the Population, Concept, Context (PCC) as well as inclusion and exclusion criteria. Article screening was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Review (PRISMA-ScR) guidelines (2020), and the Guidance for Conducting Systematic Scoping Review (2015) was followed to extract the data. Results: The search yielded 6,073 articles. Based on the screening, 8 articles were analyzed further. Most of the articles reported that prevention and screening for STIs were more common among adolescent girls. Some methods of improving STI prevention and screening include education, counselling, discussion, campaigns, the utilization of technology (tablets), and facilitator training. Conclusion: Improving STI prevention and screening among adolescents requires specific strategies and approaches. Effective strategies and approaches must take into account the developmental characteristics of adolescents, the influence of the social environment, and the role of peers in shaping health behaviors. Further research is needed to develop peer support-based interventions for adolescents to promote STI prevention and increase participation in STI screening.
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