<![CDATA[Medicine inventory management in pharmacies plays a direct role in service quality and patient safety. Improper storage and stock rotation can lead to medicine accumulation, an increase in expired medicines, and losses for pharmacies. This literature review aims to describe the application of the First In First Out (FIFO) and First Expired First Out (FEFO) methods in drug management in various pharmacies in Indonesia and the factors that influence their success. The study was conducted by reviewing ten articles that met the inclusion criteria and summarized in a table containing the location of the study, storage methods, and the main findings of each study. The results of the review show that some pharmacies have implemented FIFO and FEFO in accordance with standards with a high level of compliance, while other pharmacies still face problems with expired drugs, slow-moving drugs, and weaknesses in internal control. The implementation of an FEFO-based stock management information system, including the use of barcodes and expiration date alerts, helps improve stock rotation accuracy and reduce the risk of human error, thereby maintaining the quality of service in pharmacies.]]>
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