<![CDATA[Purpose of the study: This study aims to develop Science Literacy-Based Smart Card Media on the nervous system material for 11th-grade science students and to test its validity, practicality, and effectiveness in improving students’ science literacy skills. Methodology: The study uses a Research and Development approach based on the 4-D model, which includes the stages of define, design, develop, and disseminate. The research subjects were 35 11th-grade science students at Budisatrya Private High School, Medan. Research instruments included interview guidelines, expert-validation questionnaires, teacher and student response questionnaires, and pretests and posttests. The data were analyzed descriptively using validity percentages, practicality, N-Gain, and a paired-samples t-test. Main Findings: The research results show that the developed media received a media expert validation score of 96.42% and a material expert score of 89.06%, both of which fall into the very valid category. Practicality tests showed student responses of 95% and teacher responses of 98.14%, both categorized as very practical. Effectiveness tests showed an increase in average scores from 46 on the pretest to 90 on the posttest, with an N-Gain score of 0.81 (80.88%), categorized as high. Novelty/Originality of this study: The novelty of this research lies in integrating PISA science literacy indicators into Smart Card media by presenting scientific phenomena, contextual case studies, data interpretation, and problem-solving activities on the nervous system. Science Literacy-Based Smart Card Media is declared valid, practical, and effective, making it suitable for use as an alternative Biology learning media to support the strengthening of students’ science literacy.]]>
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